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Multiple Sclerosis clinical trials

View clinical trials related to Multiple Sclerosis.

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NCT ID: NCT06270641 Recruiting - Fatigue Clinical Trials

Increasing Physical Activity for Adults With Multiple Sclerosis (MS)

Start date: February 16, 2024
Phase: N/A
Study type: Interventional

This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients with multiple sclerosis (MS).

NCT ID: NCT06270342 Completed - Multiple Sclerosis Clinical Trials

The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients

Start date: June 1, 2023
Phase:
Study type: Observational

The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls. Additionally, another aim of our study was to compare the cognitive status, quality of life, fatigue and emotional states of individuals with MS and healthy controls.

NCT ID: NCT06267781 Recruiting - Multiple Sclerosis Clinical Trials

RRMS: Disease PROgression and Myeloid Profiling After Bone Marrow TRANSPLANTation and Second Line Therapies

TRANSPLANTPRO
Start date: September 2, 2022
Phase:
Study type: Observational

To study whether highly effective therapies can halt disease progression in people with multiple sclerosis by modulating the peripheral myeloid landscape.

NCT ID: NCT06265922 Not yet recruiting - Clinical trials for Patients With Multiple Sclerosis

Cerebellar rTMS in Patients With Multiple Sclerosis

Start date: February 18, 2024
Phase: N/A
Study type: Interventional

To determine the efficacy of high frequency cerebellar repetitive transcranial magnetic stimulation on coordination in patients with multiple sclerosis.

NCT ID: NCT06264336 Recruiting - Multiple Sclerosis Clinical Trials

Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Nearly 1 million individuals in the United States have multiple sclerosis, which causes fatigue and problems with walking. Fatigue and walking problems are poorly treated, but exercise training, particularly high-intensity walking exercise, may help. This provide insight into whether high-intensity walking exercise can improve fatigue and walking problems in people with multiple sclerosis, which could improve quality of life and reduce economic burden.

NCT ID: NCT06264037 Recruiting - Stroke Clinical Trials

The Experience in Neurorehabilitation Setting: a Qualitative Study

NURSEXPERIENCE
Start date: March 15, 2023
Phase:
Study type: Observational [Patient Registry]

In this exploratory qualitative study with a hermeneutic phenomenological approach, we will describe and understand the experience of treatment and hospitalization in hospitalized people suffering from stroke, multiple sclerosis, Parkinson's disease and patients post-neurosurgery for oncological causes. Patients will be interviewed in a semi-structured manner and sampling will take place for each of the pathology groups according to the saturation method.

NCT ID: NCT06263556 Recruiting - Multiple Sclerosis Clinical Trials

Effectiveness of TTNS in MS Patients With Lower Urinary Track Symptoms

Start date: January 17, 2024
Phase: N/A
Study type: Interventional

Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system. It is characterized with demyelinated plaques affecting subcortical, brain stem, and spinal cord nerve fibers. During the course of the disease, with the affection myelinated nerve tracks, lower urinary track symptoms may occur. 50-90% of the MS patients experience lower urinary track symptoms (LUTS) such as urinary incontinence, urgency, nocturia and/or urinary frequency during the at one point of their life. Aim of this study is to determine the effects of transcutaneous tibial nerve stimulation (TTNS) on symptoms and quality of life in MS patients with LUTS.

NCT ID: NCT06261541 Active, not recruiting - Multiple Sclerosis Clinical Trials

Clinical Investigation to Validate the Safety and Performance of the ABLE Exoskeleton Device for Individuals With Multiple Sclerosis in a Clinical Setting

Start date: April 8, 2024
Phase: N/A
Study type: Interventional

The primary objective of the study is to validate the safety and performance of the ABLE Exoskeleton device in people with multiple sclerosis during a 10-session gait training program in a clinical setting. Furthermore, the potential effects of the training on walking, and balance function, general health status, user satisfaction, and quality of life will be assessed.

NCT ID: NCT06261528 Recruiting - Clinical trials for Progressive Multiple Sclerosis

Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis

NO-FATIGUE
Start date: April 18, 2024
Phase: Phase 1
Study type: Interventional

The study is being done to determine if treatment with a novel form of light therapy is tolerated in patients with progressive multiple sclerosis. The goal of this trial to establish the safety profile of this light therapy while generating data on its impact on fatigue, as well as its mechanism of action. Fatigue is often a complex symptom in multiple sclerosis, without any FDA-approved direct therapy. Fatigue is traditionally treated with symptom management through a multidisciplinary team.

NCT ID: NCT06261489 Not yet recruiting - Multiple Sclerosis Clinical Trials

Cannabis (THC vs. CBD) in Multiple Sclerosis

Start date: March 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to examine the effect of Cannabis components, THC and CBD, on cognition and bladder symptoms in people with Multiple Sclerosis (MS). Participants will complete questionnaires and cognitive tests. They will be randomly assigned to receive either CBD or THC oil and will take the study drug for 15 weeks.