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Mobility Limitation clinical trials

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NCT ID: NCT03125447 Completed - Mobility Limitation Clinical Trials

Mobility and Attention Capacity in Former Premature Children

PAM
Start date: May 29, 2017
Phase: N/A
Study type: Interventional

Attention functions have a major impact on children's social and school behavior. They are an important issue for prematurely born children often seen as having learning difficulties and being restless, when it could be an adaptative answer to attention disorders. The aim of this study is to evaluate attention capacity in former premature children aged 6-7 years old with regards to different postures or mobility, for the attention functions of orienting, alerting and executive control. The Attention Network Test using reaction time and accuracy to visual stimuli will be used to evaluate attention functions in each posture and mobility.

NCT ID: NCT03122626 Completed - Stroke Clinical Trials

Does a Group, Task-oriented Community-based Exercise Program Improve Everyday Function in People With Stroke?

Start date: February 2, 2017
Phase: N/A
Study type: Interventional

After a stroke, people find it difficult to perform everyday activities independently, like getting dressed, preparing meals, and shopping, limiting their independence and requiring the assistance of a family member, friend or a home care worker. Losing one's independence can decrease quality of life. Functional exercise classes run by physical therapists where people with stroke practice getting in and out of a chair, stepping, and walking, can improve the ability to balance, walk, and do everyday activities. These classes are not commonly available in community centres, mainly because fitness instructors do not receive training in how to run exercise classes for people with stroke. Therefore there is a need to make these functional exercise programs available in local community centres. The objective of this project is to test procedures for running a large study to see whether people with stroke improve their ability to do everyday activities after participating in functional group exercise classes for 12 weeks in local community centres. If ability to do everyday activities improves, the investigators wish to see if the improvement is still present 3, 6 and 9 months later. Physical therapists at a nearby hospital will teach fitness instructors how to run the exercise class, help out during the classes, and answer questions by email or phone. Before conducting the larger Canada-wide study, it is important to determine the interest in such a program, the acceptability of the evaluations and the costs associated with the program, the degree of improvements resulting from the program, and if fitness instructors are able to run the program as planned. In Toronto, London and Pembroke, Canada, managers at a hospital and a nearby recreation centre have agreed to help run the exercise program. A recruiter will ask people with stroke who can walk and are being discharged home from the hospital whether they can be called about the study. People with stroke and a caregiver who agree to participate in the study will complete four evaluations when they enter the study, and 3, 6, and 12 months later. At each evaluation, people with stroke will perform tests of balance and walking, and complete questionnaires about their mood, participation in valued activities, and quality of life. After the first evaluation, the investigators will use a process like flipping a coin, to see if the person with stroke will begin the exercise program immediately or 12 months later. The investigators will call people each month to ask if a fall occurred. The investigators will interview exercise participants, family members and hospital/recreation staff at the end of the study to ask about the experiences. This project is unique because the program combines the expert knowledge and skills of physical therapists and fitness instructors. The exercise program involves practicing everyday movements, making the exercises easy for fitness instructors and people with stroke to learn. Each exercise has multiple levels of difficulty so the instructor can adapt exercises to how the person is feeling. The exercise program does not require expensive equipment (e.g. chairs, stepping stools) and therefore can be offered in most community centres. Finally, an extensive network of hospitals providing stroke care and community centres run by recreation organizations exists in Canada. Thus, if this program is beneficial, it could easily be made widely available. With the number of Canadians living with the consequences of stroke increasing every year, access to a functional exercise programs in local community centres will improve their ability to function and live independently in the community and reduce the burden on family or caregivers and on the healthcare system.

NCT ID: NCT03122236 Completed - Clinical trials for Cognitive Impairment

Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

Loss of mobility and cognitive ability are serious conditions that threaten the independence of older adults. The objective of this study is to initiate a line of research to develop a novel therapeutic intervention to enhance both mobility and cognition via neuroplasticity of frontal/executive circuits.

NCT ID: NCT03083275 Completed - Mobility Limitation Clinical Trials

Resistance Training in Older Adults With Limitations in Mobility

TRANS2
Start date: January 3, 2016
Phase: N/A
Study type: Interventional

The age-related loss in skeletal muscle mass is associated with substantial social and economic costs as evidenced by impairments in strength, limitations in function, and ultimately, physical disability and institutionalization (1-3). Improved knowledge of the physiologic mechanisms that mediate impairments in physical functioning is crucial for developing effective therapeutic interventions for preserving mobility and independence among physically frail adults. To date, pharmacodynamic markers that can be used in a clinical trial in mobility-limited older adults are limited. Lean body mass measured by dual energy X-ray absorptiometry (DXA) is frequently used in early phase clinical development of investigational anabolic drugs. Although increase in muscle mass is considered to contribute to increased muscle strength, this alone does not completely explain changes in physical performance. Thus, more direct pharmacodynamic evidence associated with physical functioning is desired in early phase clinical development decision making. Assessments of muscle power and fatigue can address this need. The use of such assessments may provide more meaningful information as to the pharmacodynamics effects of investigational drugs on muscle parameters. This study will serve as a validation study, aiming to 1) examine the effect a 12-week resistance program may have on muscle power and fatigue; 2) examine the effect of a 12-week resistance exercise program on conventional measures of muscle function; 3) determine the relationship between muscle power/fatigue and conventional measures of physical function. Data from this study will serve as rationale for potentially including these measures as pharmacodynamics markers in studies of novel therapies for skeletal muscle loss and/or weakness.

NCT ID: NCT03071562 Completed - Depression Clinical Trials

A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV

Start date: January 2017
Phase: N/A
Study type: Interventional

Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and quality of life. Problems with memory and thinking are also associated with forgetting to take anti-retroviral drugs and experiencing challenges to balance, walking and mental health (anxiety and depression). There is increasing evidence that, in the general population, exercise has positive effects on cognition, physical functioning and mental health. Despite the recognition of multiple therapeutic benefits of exercise, little attention has been paid to its possible effects on cognition in people living with HIV. The purpose of the proposed pilot study is to compare the effects of a 12-week, randomly assigned, community-based yoga-mindfulness intervention on cognition, balance, walking, mental health and quality of life in 30 people >35 years of age living with HIV in the Halifax area. Yoga is of particular interest because it encompasses not only the physical but also spiritual, emotional, and mental dimensions of life. As such, it has tremendous potential to help stave off some of the devastating consequences of HIV infection.

NCT ID: NCT03032341 Completed - Mobility Limitation Clinical Trials

Mobility Assessment Using Surrogates in Elderly Participants

MAT
Start date: January 17, 2017
Phase: N/A
Study type: Observational

The purpose of this research study is to find out if mobility (the ability to move around) can be reliably assessed by having the family or care giver caregiver take a video based test for the patient. If this study shows that mobility can be assessed by family or caregiver, this information can be used in situations where mobility cannot be measured directly in patients. A total of 60 patients and 60 family/caregivers at Wake Forest Baptist Medical Center will take part in this study. Patients physical function will be assessed using a test that uses short movie clips to assess mobility. Patients will be asked to watch ten short (~10 seconds each) movie clips that describe various tasks such as climbing up hills or walking and estimate if they can perform the tasks. The familymember/caregiver will be also asked to answer the questions on behalf of the patient. The family member/caregiver will be asked to return to take the same test in the next 1-14 days. The patient will be in the study for one day. There is no intervention, this is observational.

NCT ID: NCT02947230 Completed - Mobility Limitation Clinical Trials

Evaluating the Impact of the McMaster Optimal Aging Portal on Physical Mobility Outcomes

Start date: March 7, 2017
Phase: N/A
Study type: Interventional

The McMaster Optimal Aging Portal (the Portal) was launched in 2014 to increase public access to trustworthy health information. The Portal helps readers to access evidence-based resources; identify trustworthy messages; and understand scientific findings. Now the investigators want to know whether using the Portal changes what people know and do to stay healthy and mobile. This project will help us to: 1. Understand how middle aged and older adults (age 40+) use the Portal to obtain information about maintaining and improving mobility 2. Evaluate whether use of the Portal results in a change in knowledge about maintaining and improving mobility, or change in lifestyle behaviours that may help maintain or improve mobility with age.

NCT ID: NCT02913976 Completed - Mobility Limitation Clinical Trials

Changes on Pain and Range of Motion by the Use of Kinesio Taping in Patients Diagnosed With Cervical Pain

Start date: October 2016
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate that the application of Kinesio Taping on a myofascial trigger point in the trapezius muscle able to cause a decrease of the pain and an increase of the cervical range of motion in patients diagnosed with cervical pain.

NCT ID: NCT02913963 Completed - Mobility Limitation Clinical Trials

Changes on Pain and Range of Motion by the Use of Kinesio Taping in Subjects With Myofascial Trigger Point

Start date: October 2016
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate that the application of Kinesio Taping on a myofascial trigger point in the trapezius muscle able to cause a decrease of the trigger point pain and an increase of the cervical range of motion in asymptomatic subjects

NCT ID: NCT02901444 Completed - Mobility Limitation Clinical Trials

Observational Study on Changing the Quality of Life in Daily Life Activities After Clinical Approach Positioning the Wheelchair

Start date: March 2015
Phase: N/A
Study type: Observational

Stemming from the common practice of attribution of the technical helps in the posture in Canada, the multidisciplinary approach of positioning develops in France for more than 10 years old. To date, no observatory study was led to estimate the impact of such consultation in daily activities, an essential objective conditioning the observance and the acceptance of assistive devices. This study wants to estimate the impact through modification of WHOM scale.