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Clinical Trial Summary

This is a Phase 1b/2, multiple-dose study designed to describe safety and efficacy, and to assess PK and immunogenicity of XmAb18087 monotherapy and in combination with pembrolizumab in participants with metastatic Merkel cell (MCC) or locoregional MCC that has recurred after locoregional therapy with surgery and/or radiation therapy, and mAb18087 monotherapy in participants with extensive-stage small cell lung cancer (SCLC) that has progressed after standard therapies. This study was terminated by the sponsor. No participants enrolled in Part B.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04590781
Study type Interventional
Source Xencor, Inc.
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date May 10, 2021
Completion date March 24, 2022

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