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mCRC clinical trials

View clinical trials related to mCRC.

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NCT ID: NCT05690035 Not yet recruiting - Clinical trials for Metastatic Colorectal Cancer

Tislelizumab Combined With Fruquintinib for Metastatic pMMR/MSS Colorectal Cancer

Start date: February 2023
Phase: Phase 2
Study type: Interventional

This is an open-label phase II study, with the aim of investigating the efficacy and safety of Tislelizumab + Fruquintinib combination therapy in ARID1A-mutated pMMR/MSS metastatic colorectal cancer who have been treated with standard chemotherapy that includes fluoropyrimidine, oxaliplatin, and irinotecan. Patients with hypermutated CRC that carries POLE/POLD1 mutations cannot be included.

NCT ID: NCT05127759 Active, not recruiting - Clinical trials for Metastatic Colorectal Cancer

The Efficacy and Safety of HLX208 in Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation

Start date: March 23, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study was to assess efficacy, safety and PK in metastatic colorectal cancer (mCRC) given HLX208 (BRAF V600E inhibitor).

NCT ID: NCT03567629 Active, not recruiting - mCRC Clinical Trials

Evaluate the Efficacy of Irinotecan Versus Oxaliplatin in the First-line Treatment of Refractory Metastatic Colorectal Cancer

Start date: May 29, 2018
Phase: Phase 2
Study type: Interventional

This is a prospective, open-lable, multicenter, randomized, controlled, phase II clinical study. The aim is to evaluate the efficacy of Irinotecan versus Oxaliplatin in the first-line treatment of refractory metastatic colorectal cancer.

NCT ID: NCT03563157 Active, not recruiting - Clinical trials for Colorectal Cancer Metastatic

QUILT 3.071: NANT Colorectal Cancer (CRC) Vaccine

Start date: May 25, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

QUILT 3.071 NANT Colorectal Cancer (CRC) Vaccine: Phase 1b/2 NANT CRC Vaccine vs Regorafenib in Subjects with CRC Who have Previously Treated with SOC.

NCT ID: NCT02547480 Completed - Clinical trials for Metastatic Colorectal Cancer

LifePearl-Iri Pharmacokinetic Study

Start date: November 2015
Phase: N/A
Study type: Interventional

The primary purpose of the study is to evaluate the pharmacokinetic profile, safety, and efficacy of LifePearl microspheres loaded with irinotecan in the treatment of liver predominant mCRC by chemoembolization.