Mantle Cell Lymphoma Clinical Trial
Official title:
Bendamustine, Lenalidomide and Rituximab (R2-B) Combination as a Second-Line Therapy for First Relapsed-Refractory Mantle Cell Lymphomas: A Phase II Study
This is a prospective, multicenter phase II trial designed to evaluate the safety and activity of the combination of Bendamustine, Lenalidomide and Rituximab (R2-B) in patients with first relapsed/refractory mantle cell lymphoma (MCL) and the efficacy and safety of a maintenance treatment with Lenalidomide for 18 months from the end of R2-B (from month 7 to 24) for those responding to the induction.
This is a phase II study, non randomized, multicenter. Patients with MCL refractory to front
line therapy or in first relapse will be enrolled.
The study includes an induction phase, a consolidation phase, a maintenance phase and a
follow up phase.
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