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Malocclusion clinical trials

View clinical trials related to Malocclusion.

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NCT ID: NCT05532241 Recruiting - Gingivitis Clinical Trials

Dental Biofilm Control During Orthodontic Treatment

ORTHOBIOFILM
Start date: November 1, 2021
Phase: Phase 3
Study type: Interventional

Orthodontic appliances can affect changes in the relationships of members of the oral microbiome. Microbiome imbalance can result in oral infections and complicate treatment. The focus is on the microbiological profile of dental biofilm and its control. The effects of metals released by corrosion of alloys for oral use on the microbiome and the extent to which they modify the effectiveness of gingivitis therapy by mechanical and chemical control of biofilm will be investigated. Early and late colonizers of the tooth surface will be analyzed. The condition of gingiva will be assessed, and the results will show the specifics of biofilm and gingiva exposed and unexposed, and differences in the response of individual bacteria to therapy. Molecular biology techniques will be used to quantify the total bacterial biomass (16s rRNA) and the proportion of specific bacterial species within the dental biofilm.

NCT ID: NCT05499221 Recruiting - Clinical trials for Malocclusion, Angle Class II

Bone Anchored Carriere Motion Appliance

Start date: January 26, 2022
Phase: N/A
Study type: Interventional

Carriere Motion appliance (CMA) was designed to change a Class II molar relationship into a Class I relationship by distalizing the whole posterior maxillary segment by means of class II elastics and mandibular anchorage. To eliminate the adverse effects of CMA with class II elastics, we can use the CMA to distalize the maxillary posterior segment with intra-arch anchorage using infrazygomatic miniscrews. The aim of this study is to evaluate skeletaly anchored CMA for distalization of the maxillary buccal segment vs. conventionally anchored CMA by comparing skeletal and dental measurements obtained from lateral cephalometric radiographs obtained prior to treatment (T0) and immediately after correction of class II and remval of the appliance (T1).

NCT ID: NCT05465473 Recruiting - Clinical trials for Class II Division 1 Malocclusion

Effect of Low-level Laser Therapy During Maxillary Molar Distalization Using a Skeletally Anchored Appliance

Start date: December 12, 2021
Phase: N/A
Study type: Interventional

study will be directed to evaluate the effect of low-level laser therapy during maxillary molar distalization using a skeletally anchored appliance

NCT ID: NCT05441683 Recruiting - Malocclusion Clinical Trials

Comparing of the Clinical Outcome of Periodontal Accelerated Osteogenic Orthodontics With Horizontal or Vertical Releasing Incisions

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The study aims to compare the effect of periodontal accelerated osteogenic orthodontics (PAOO) with horizontal or vertical releasing incisions on operation time, healing, adverse effects, and effectiveness of bone augmentation. Methods: A total of 22 patients requiring PAOO surgery due to orthodontic treatment were enrolled in this trial, and randomly divided into test or control group, consisting of 11 subjects in each. The test group will receive PAOO with horizontal extending incisions on both sides of the flap; while the control group will receive PAOO with vertical releasing incisions; the two groups use the same surgical technic except for the incision design. Outcome measures include: operation time, postoperative scar, radiographic data (alveolar height and alveolar ridge thickness), gingival thickness, etc. Clinical evaluation will be performed at 1 week, 2 weeks, 3months, 6 months and 12 months after operation.

NCT ID: NCT05383820 Recruiting - Pain, Acute Clinical Trials

Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment

Start date: September 27, 2021
Phase: Phase 4
Study type: Interventional

Due to the high prevalence of malocclusions in Mexico and the existing concern to improve aesthetics, function (chewing), or both, patients resort to orthodontic treatment. The patient may experience pain during treatment due to the release of different chemical mediators such as RANK-L. Analgesic and anti-inflammatory medications such as acetaminophen and ketorolac are used to control pain during orthodontic tooth movement. These drugs can inhibit the expression of RANK-L which can affect tooth movement, inhibiting bone remodeling. The orthodontist should indicate the drug that is safest for the patient without affecting treatment or tooth movement.

NCT ID: NCT05361863 Recruiting - Clinical trials for Treating Class II Malocclusion and Bimaxillary Proclination

Canine Retraction Using Different Bracket Slots' Sizes

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Primary Objective Evaluating the effectiveness of canine retraction in terms of: rate of movement and rotation using 0.020-inch slot and dual-slot systems in comparison with the 0.022-inch slot system. Secondary Objectives - Measuring the amount of molar anchorage loss during canine retraction between the different bracket slot appliances. - Evaluation of alignment efficiency using different bracket slot appliances. Null Hypothesis There is insignificant difference in the effectiveness of canine retraction with different bracket slot size appliances. • Evaluation of the bracket slot and archwire dimensions precision

NCT ID: NCT05361616 Recruiting - Malocclusion Clinical Trials

Impact of Photobiomodulation on Pain During Orthodontic Treatment.

Start date: April 17, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to determine to effect of PBM Ortho, a photobiomodulation device, in adult patients undergoing clear aligners orthodontic treatment. We hypothesize that PBM Ortho will reduced the orthodontic associated pain in the clear aligner patients. This effect will be evaluated by recording the pain on visual analog scale given to the patients before the placement of clear aligners and collecting saliva.

NCT ID: NCT05333094 Recruiting - Clinical trials for Crowding, Tooth, Class I

Comparison Between the Effectiveness of Different Commercial Bracket Brands

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

There's a scarcity in literature concerning the comparison of the effectiveness of brackets in its torque and tip ability, the time takes for leveling and alignment comparing between different orthodontic bracket brands, and its effect on the rate of tooth movement. The purpose of this study is to determine, In orthodontic patients with Class I molar relation and teeth crowding, in which different bracket brands will be compared.

NCT ID: NCT05227469 Recruiting - Clinical trials for Malocclusion, Angle Class II

Myofunctional Therapy Twin Block

twin block
Start date: October 18, 2021
Phase: N/A
Study type: Interventional

There are situations where orthodontic treatment cannot provide long-term benefits. The proposed orthotropic theory proposes that environmental factors cause malocclusion and genes decide its pattern. The primary aim of this project is to increase the success, aesthetics and permanence of the treatment result by providing the best facial change of the pediatric patients in the MP3cap period, and that myofunctional exercises can be used in addition to orthodontic treatments during the treatment process of the patients.

NCT ID: NCT05216874 Recruiting - Clinical trials for Class III Malocclusion

The Effect of Splint Usage in Laterognathic Cl III Orthognathic Surgery Patients

TMJ
Start date: January 13, 2022
Phase: N/A
Study type: Interventional

It is crucial to maintain the anatomic condylar positions during orthognathic surgery. Condylar positions are affected directly under general anesthesia because of joint and muscle relaxation. Possible unwanted changes in the joint position may cause incorrect positioning of the jawbones. This could affect the success of the surgery in terms of function and facial aesthetics causing the need for a second surgery. Our aim is to evaluate whether the use of MR Splint has a statistically significant effect on muscle relaxation-induced condyle position deviations under general anesthesia in Class III Laterognathia patients.