Modified Melanoma Vaccine for High Risk or Low Residual Disease Patients

Status Recruiting

Clinical Trial Summary

This study is designed for patients who had malignant melanoma and, following tumor removal, are now free of disease, or have only very minor residual disease, and are at a very high risk of disease recurrence. These patients will be treated with the A2/4-1BBL melanoma vaccine, a compatible melanoma cell line that has been engineered to express a molecule termed 4-1BBL, which enhances the chances of the cell line to be recognized by the patient's immune system, and to induce its stimulation. The hypothesis that drives the study states that the immune response against the cell line will also be effective against the residual tumor that may still be present in the body.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01898039
Study type	Interventional
Source	Hadassah Medical Organization
Contact	Hani Steinberg, RN
Phone	972507874292
Email	hanis@hadassah.org.il
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	May 2013
Completion date	April 2019

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