Macular Degeneration Clinical Trial
Official title:
A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degeneration
The general objective of this study is to evaluate the safety and efficacy of ophthalmic intravitreal injections of ALG-1001 in human subjects with wet age-related macular degeneration (Wet AMD). This study builds upon the safety and efficacy results of numerous animal studies and an earlier Phase I Human Study in end-stage diabetic macular edema patients.
The general objective of this study is to evaluate the safety and efficacy of ophthalmic
intravitreal injections of ALG-1001 in human subjects with wet age-related macular
degeneration (Wet AMD). This study builds upon the safety and efficacy results of numerous
animal studies and an earlier Phase I Human Study in end-stage diabetic macular edema
patients.
The specific objective of this six-month study is to evaluate the safety and efficacy of
three monthly ophthalmic intravitreal injections of ALG-1001 in human subjects with Wet AMD,
and to follow these subjects for an additional four months off-treatment. Three cohorts have
been established as part of the study design, utilizing three different doses.
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