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Lymphoma clinical trials

View clinical trials related to Lymphoma.

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NCT ID: NCT05977673 Not yet recruiting - Hodgkin Lymphoma Clinical Trials

Efficacy and Safety of Frontline Tislelizumab in Patients With de Novo Hodgkin Lymphoma Unsuitable for Standard Frontline Chemotherapy

FIL_Tisle-HL
Start date: December 2023
Phase: Phase 2
Study type: Interventional

This is a multicenter, prospective, non-randomized, open-label, phase 2 clinical study to evaluate the efficacy and safety of tislelizumab in patients with de novo Hodgkin Lymphoma deemed ineligible to frontline chemotherapy.

NCT ID: NCT05969821 Not yet recruiting - Lymphoma Clinical Trials

Clonal Hematopoiesis of Immunological Significance

CHIS
Start date: September 2023
Phase:
Study type: Observational [Patient Registry]

Ambispective, national, multicenter observational cohort study aimed at characterizing the satellite dysimmune manifestations of clonal hematopoiesis, including Vexas (Vacuoles, E1 enzyme, X-linked, Autoinflammatory and Somatic) syndrome.

NCT ID: NCT05968001 Not yet recruiting - Clinical trials for Lymphomas Non-Hodgkin's B-Cell

Obinutuzumab in Chinese Real-world Patients With iNHL

Start date: July 20, 2023
Phase:
Study type: Observational

This study aims to assess the clinical efficacy and safety of obinutuzumab in Chinese patients with indolent non-Hodgkin B-cell Lymphoma (predominantly Follicular lymphoma and Marginal zone lymphoma) in a real-world setting.

NCT ID: NCT05967975 Not yet recruiting - Lymphoma Clinical Trials

Elastography and Treatment of Lymphoma

Start date: August 2023
Phase:
Study type: Observational

To determine accuracy of elastography in assessment of superficial lymph nodes response to treatment in cases of lymphoma.

NCT ID: NCT05952024 Not yet recruiting - Clinical trials for Diffuse Large B-Cell Lymphoma

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

ACRUE
Start date: March 29, 2024
Phase: Phase 2
Study type: Interventional

The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBCL), who are otherwise unsuitable for standard front line chemoimmunotherapy treatments.

NCT ID: NCT05949931 Not yet recruiting - Clinical trials for Classic Hodgkin Lymphoma

Pianzumab Combined With AVD Regimen in the Treatment of Newly-diagnosed Advanced Classic Hodgkin Lymphoma

Start date: August 2023
Phase: Phase 2
Study type: Interventional

This study is conducted to evaluate the safety and efficiency of Penpulimab combined with AVD in patients with newly- diagnosed advanced classic Hodgkin lymphoma.

NCT ID: NCT05936229 Not yet recruiting - Clinical trials for Recurrent Mantle Cell Lymphoma

Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell Therapy

Start date: April 1, 2025
Phase: Phase 1/Phase 2
Study type: Interventional

This phase I/II trial tests the safety and how well intravenous interferon-beta-1a (FP-1201) works in preventing toxicities after CD19-directed chimeric antigen receptor (CAR) T-cell therapy in patients with B-cell cancers that has come back after a period of improvement (recurrent) or that has not responded to previous treatment (refractory). Interferon beta-1a is in a class of medications called immunomodulators. It works by protecting the lining of blood vessels, and preventing brain inflammation. Giving FP-1201 may prevent cytokine release syndrome (CRS) and immune effector cell associated-neurotoxicity syndrome (ICANS) toxicities in patients receiving CD19 CAR T-cell therapy with recurrent or refractory B-cell malignancies.

NCT ID: NCT05934084 Not yet recruiting - Clinical trials for Classical Hodgkin Lymphoma

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

This is a prospective randomized open-label, multicenter, 2-arm study to assess the role of healthy LifeStyle implemented Survivorship Care Plan (LS-SCP) in modifying the Quality of Life (QoL) in a population of long-term lymphoma survivors (in remission for a minimum 3 years since the last treatment and a maximum of 10 years).

NCT ID: NCT05923879 Not yet recruiting - Clinical trials for Lymphoma, Large B-Cell, Diffuse

Mechanism Investigation of Selinexor Combined With Lenalidomide and Rituximab in the Treatment of Diffuse Large B-cell Lymphoma

Start date: June 30, 2023
Phase:
Study type: Observational

This is a retrospective observational study of the therapeutic mechanism and resistance mechanism of the treatment of Selinexor combined with lenalidomide and rituximab in diffuse large B-cell lymphoma patients. By detecting the immune cells in peripheral blood and tumor tissues of patients before and after treatment, the key immune cell subsets and immune molecules linked to the action and resistance of the treatment of Selinexor combined with lenalidomide and rituximab, so as to provide the basis for the optimization of the treatment or the combination of other immunotherapies.

NCT ID: NCT05923502 Not yet recruiting - Follicular Lymphoma Clinical Trials

(CHANT)Real World Study of Duvelisib in the Treatment of Non-Hodgkin's Lymphoma (NHL)

Start date: October 20, 2023
Phase:
Study type: Observational

This is a multicenter, non-interventional and prospective real-world study to evaluate the efficacy and safety of Duvelisib capsules in patients with non-Hodgkin's lymphoma.