Lumbar Disc Herniations Clinical Trial
Official title:
Detection of Bacteria in Herniated Nucleus Material in Lumbar Disc Herniations by Culture and PCR
The aim is to investigate if herniated nucleus material in lumbar disc herniations is
infected with bacteria, and if so, to determine their prevalence (control group), and to
determine if patients with pre-existing Modic changes type 1 have a higher incidence of
bacterial growth in relevant lumbar disc samples than patients without Modic changes.
A cohort of 15 patients with pre-existing Modic and 15 without-undergoing primary surgery
will be examined.
The nucleus material will be evacuated and divided into 5 biopsies, each with a new set of
sterile instruments and placed in separate sterile glass vials with one drop of sterile
saline to prevent drying of biopsy.
The primary outcome, i.e., bacterial growth on a per-patient basis. Bacterial growth shall be
detected in minimum 3 out of 5 biopsies for the patient to be scored as positive for
bacteria.
;