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Low Back Pain clinical trials

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NCT ID: NCT02922322 Completed - Clinical trials for Chronic Low Back Pain

Effectiveness of Mat Pilates Exercises in Individuals With Chronic Nonspecific Low Back Pain

Start date: February 2016
Phase: N/A
Study type: Interventional

To analyze the effectiveness of mat Pilates compared to no intervention in individuals with chronic nonspecific low back pain.

NCT ID: NCT02921490 Completed - Low Back Pain Clinical Trials

FDG PET/MRI Evaluation of Facet Joint Pain

Start date: September 2016
Phase: N/A
Study type: Interventional

Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints. The clinical evaluation of facet joints is challenging and anatomic imaging findings of facet joint; degenerative change; correlate poorly with pain. Therefore, it is difficult to select appropriate candidate patients/facet joints to treat. Misguided percutaneous treatment can cost thousands of dollars per session and delay diagnoses. Very limited retrospective information suggests that high grade peri-facet MRI signal change correlates to the side of LBP. However, this has not fully characterized the imaging findings and has not correlated to expert clinical exam/percutaneous response, precluding robust and meaningful clinical impact. Minimal retrospective data concludes inflammatory changes can be identified on FDG-PET exams, but the evidence of correlation to patient pain is lacking. Limited DWI exists for inflammatory spondyloarthropathies and myopathies, but is also lacking. This is an exploratory study investigating the utility of FDG PET activity and MRI signal change around facet joints in the clinical management of low back pain. This study will help determine if such imaging biomarkers could change clinical management. Additionally, this will provide data that will be vital to planning a larger prospective study evaluating the ability of imaging biomarkers to predict response to comparison medial branch blocks and RF ablation for treatment of facet joint pain.

NCT ID: NCT02906540 Completed - Low Back Pain Clinical Trials

Transpubic Symphysis Reset for Treatment of Low Back Pain

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

To verify the efficacy of transpubic symphysis reset therapy for low back pain, and provide support for the clinical application of this treatment.

NCT ID: NCT02901327 Completed - Clinical trials for Chronic Low Back Pain

Multifidus Activation, Pain and Functional Disability in Individuals With Chronic Low Back Pain

CMLBP
Start date: March 2015
Phase: N/A
Study type: Interventional

Chronic Mechanical Low Back Pain (CMLBP) is a common disabling health problem among the general population. Multifidus muscle inhibition accompanying CMLBP plays a major role in perpetuating the pain and functional disability. Lumbar stabilisation and treadmill exercises are established treatments for CMLBP. However, it is not known which of the two techniques is more effective. This study was conducted to compare the effects of lumbar stabilisation and treadmill walk on multifidus activation, pain and functional disability in individuals with CMLBP.

NCT ID: NCT02897973 Completed - Low Back Pain Clinical Trials

The Impact of Unilateral Lower Limb Amputation on Spinal Loads

Start date: September 2011
Phase:
Study type: Observational

The prevalence of low back pain among persons with unilateral lower limb amputation is significantly higher than the rate experienced by the general public. Chronic pain, including low back pain, limits functional independence and negatively impacts quality of life. As such, this project will investigate the role of a biomechanical casual pathway in the development of low back pain; to do this, the investigators will explore the relationship between the adopted neuromuscular patterns post-amputation to perform activities of daily living and the risk of developing spinal tissue damage.

NCT ID: NCT02895828 Completed - Clinical trials for Chronic Low Back Pain

Effects of Core Stabilization and Strengthening Exercise on Quality of Life in Clinical Lumbar Instability

Start date: August 2016
Phase: N/A
Study type: Interventional

This study will compare the effects of 2 exercise programs including core stabilization exercise and general trunk strengthening exercise programs on trunk muscle activity, physical dysfunction, quality of life and lumbar motion in low back pain patient with clinical lumbar instability.

NCT ID: NCT02895555 Completed - Low Back Pain Clinical Trials

The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Fusion The IVANOS-study

IVANOS
Start date: March 2012
Phase: N/A
Study type: Interventional

The average life expectancy in Denmark is increasing resulting in an increasing part of the population having age-related disease, ex lumbar spinal stenosis (LSS). LSS causes constriction of the nerves in the lumbar spine resulting in pain in the legs and lower back, especially when standing and walking, known as neurogenic claudicatio(Goh KJ FAU - Khalifa et al.). LSS occurs in a combination of degenerative changes in the lower back, including hypertrophy of the ligamentum flavum, arthrosis of the facet joints and bulging of the disc. Current treatment of LSS is varied ranging from non-operative conservative treatment to operation. Operative intervention shows very good results according to physical ability and pain(Christensen FB et al.;Hee HT and Wong;McGregor AH FAU - Hughes and Hughes;Xu et al.), but the most optimal treatment is still debated. Nevertheless, a decompression and, if needed, a spinal fusion is recommended. The investigators want to se whether i-FACTOR improves clinical outcomes compared to using allograft in spinal fusion in the elderly, and thereby find an improved methods operating this difficult patient population. The hypothesis is, that there is no difference in clinical outcomes whether you use i-FACTOR or allograft i non-instrumented spinal fusion surgery in patients with spinal stenosis due to degenerative listhesis.

NCT ID: NCT02894125 Completed - Clinical trials for Chronic Low Back Pain

Evaluation of the Effectiveness of a SPA Therapy to "Neyrac-les-Bains" to the Old Subject (60-80 Years Old) With a Chronic Low Back Pain.

Start date: July 2015
Phase: N/A
Study type: Observational

Low back pain is considered to be chronic if it has been present for longer than three months. This pathology is extremely frequent with an annual incidence between 5 in 10 % of the general population. Thus she is frequently met in general medicine, in particular to the ageing subject. It is the 2nd motive for consultation. The Chronic Low Back Pain is a mild pathology the forecast of which is in the favorable great majority of the cases but she pulled a socioeconomic cost mattering with a poly-consumption of care, in private individuals. The primary objective of this study is to determine the impact of a 3 months SPA Therapy on the Chronic Low Back Pain in older adults (from 60 to 80 years old) realizing a SPA Therapy of 3 weeks to "Neyrac-les-Bains".

NCT ID: NCT02892656 Completed - Low Back Pain Clinical Trials

Reliability and Responsiveness of One Questionnaire Used on a Low Back Pain Population

Start date: August 10, 2017
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to determine the reliability and responsiveness of the Pain Self-Efficacy Questionnaire (PSEQ) in a chronic low back pain (CLBP) population referred to The Danish Rheumatism Associations´ rehabilitation centre Sano Aarhus.

NCT ID: NCT02890810 Completed - Back Pain Clinical Trials

Predicting Analgesic Response to Acupuncture: A Practical Approach

Start date: July 2016
Phase: N/A
Study type: Interventional

In this placebo controlled, patient and assessor blinded clinical trial, the investigators will administer electroacupuncture vs sham electroacupuncture to patients suffering from chronic low back pain, and monitor their symptoms as well as collecting objective outcome measures. The investigators objective is to identify predictors of pain reduction and functional improvement with electroacupuncture vs placebo.