Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester

Listeria Monocytogenes Clinical Trial

Official title:

Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester of Pregnancy: a Case Report and Review of Literatures

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03248973
• Other study ID #: 106030-C
• Status: Completed
• Start date: April 3, 2017
• Est. completion date: February 2, 2018

Study information

• Verified date: February 2019
• Source: Far Eastern Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester of Pregnancy

Description:

A 34-year-old nulliparous woman with 11 gestational weeks with flu-like illness was proved to be infection by Listeria monocytogenes, and then treated by intravenous ampicillin 2 g every 4 hours for 3 weeks. A healthy unaffected male baby was delivered at 41 weeks' gestation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1
• Est. completion date: February 2, 2018
• Est. primary completion date: January 8, 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• One pregnant woman with listeria monocytogenes bacteremia in the first trimester

Related Conditions & MeSH terms

• Bacteremia
• Listeria Monocytogenes

Intervention

Drug:
• Ampicillin Injection
Ampicillin injection 2 g q4h for 3 weeks

Locations

Country	Name	City	State
Taiwan	Far Eastern Memorial Hospital	New Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Successful treatment	A favorable outcome of maternal listeria infection in the first trimester may be anticipated. Besides, intravenous ampicillin with or without gentamicin should be a reasonable treatment option for maternal listeria infection in the first trimester.	1 month after delivery