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Clinical Trial Summary

The objective of this study is to determine if an opioid-free general anesthetic (OFA) technique utilizing lidocaine, ketamine, dexmedetomidine and magnesium reduce postoperative opioid consumption and speed return of bowel function in patients undergoing elective, laparoscopic, colorectal surgery compared to traditional opioid-containing general anesthetic techniques. It is hypothesized that this intraoperative OFA regimen will reduce postoperative opioid consumption, and expedite return of bowel function in this population.


Clinical Trial Description

The objective of this trial is to determine whether an opioid-free general anesthetic can help reduce postoperative opioid consumption and speed return of bowel function in patients undergoing elective, laparoscopic, colorectal surgery when compared with traditional opioid-containing techniques. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04144933
Study type Interventional
Source University of Saskatchewan
Contact Jonathan Gamble, MD
Phone 306-655-1183
Email jonathan.gamble@saskhealthauthority.ca
Status Recruiting
Phase Phase 3
Start date May 15, 2021
Completion date August 1, 2024

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