Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Change in average dosing interval time |
PTC(post-tetanic count)was measured every 6min during the operation, and cisatracurium was injected once when PTC > 2,average dosing interval time was recorded |
during the surgery |
|
Primary |
Change in Times of adding cisatracurium |
PTC was measured every 6min during the operation, and cisatracurium was injected once when PTC > 2,and recording the total times of injection. |
during the surgery |
|
Primary |
Change in total dosage of cisatracurium |
PTC(post-tetanic count) was measured every 6min during the operation, and cisatracurium was injected once when PTC > 2,and recording the total dosage of total dosage of cisatracurium |
during the surgery |
|
Primary |
Change in time of onset |
0.15mg/kg (3ED95) cisatracurium was given to all groups according to actual body weight as induction dose. Tracheal intubation was performed in all groups when TOFr(train of four ratio)=0.recording the time during this process. |
through study completion, an average of 3 minute after induction |
|
Primary |
Change in TOF(train of four) recovered to 0.7 and 0.9 from the last injection |
The recovery of TOF(train of four) was continue observed after surgery.Recording the time both when TOF(train of four) recovered to 0.7 and 0.9 |
up to 1 hour after the surgery |
|
Primary |
Change in time during PACU(postanesthesia care unit) |
recoding the duration of stay in PACU(postanesthesia care unit) |
up to 2 hour after the surgery |
|
Primary |
surgical rating scale(SRS) |
Surgical rating Scale (SRS) was evaluated by surgical surgeons at the beginning, 1h and 2h of surgery, with a range of 1 to 5, corresponding to "extremely poor", "poor", "adequate", "good" and "best". |
during the surgery |
|
Secondary |
The change of MAP (mean arterial pressure) |
Mean arterial pressure were recorded immediately , 10 minutes , 20 minutes , 30 minutes , and 40 minutes later after the first injection |
immediately , 10 minutes , 20 minutes , 30 minutes and 40 min later after the first injection |
|
Secondary |
The change of HR(heart rate) |
the heart rate were recorded immediately , 10 minutes , 20 minutes , 30 minutes , and 40 minutes later after the first injection |
immediately , 10 minutes , 20 minutes , 30 minutes and 40 min later after the first injection |
|
Secondary |
Change in PaCO2 before and after pneumoperitoneum |
arterial blood gas(ABG) was measured before and after pneumoperitoneum.Recording PaCO2 before and after pneumoperitoneum |
before and after pneumoperitoneum during the surgery |
|
Secondary |
Incidence of postoperative pain |
Incidence of postoperative pain (shoulder, lumbar abdomen, arm) |
Immediately after surgery and One day after surgery |
|
Secondary |
Whether hypoxemia occurs after extubation |
Observe the occurrence of hypoxemia after extubation |
within 10 minutes after extubation |
|