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Labor Pain clinical trials

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NCT ID: NCT02062801 Completed - Labor Pain Clinical Trials

Prophylactic Ephedrine and Combined Spinal Epidurals for Labor

CEASE
Start date: January 2012
Phase: Phase 4
Study type: Interventional

The combined spinal epidural (CSE) technique has become increasingly popular for labor pain because of its rapid onset and superior first stage analgesia. However, increased risk for early profound fetal bradycardia (EPFB) following CSE continues to be a concern. Various factors are implicated in the etiology of EPFB but the cause is unknown. Ephedrine administration prior to CSE analgesia may help reduce the risk of EPFB, but to date, nobody has studied the impact of a single dose of intravenous (IV) ephedrine given at the time of CSE administration during labor. The purpose of this study is to measure the incidence of EPFB after combined spinal epidural analgesia using standard definitions. The incidence of EPFB will be compared between patients who receive prophylactic ephedrine or placebo at the time of CSE placement.

NCT ID: NCT02008591 Completed - Clinical trials for Laboring Women Requesting Neuraxial Labor Analgesia

Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes

Start date: November 26, 2013
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to compare the onset and duration of the initial dose of medications given through three different epidural (conventional epidural, combined spinal epidural and dural puncture epidural) techniques for labor pain relief. The secondary objective of this study is to compare the fetal effects of these three epidural labor analgesia techniques.

NCT ID: NCT01861821 Completed - Labor Pain Clinical Trials

Analgesic Efficacy of a Multiport Versus Uniport Flexible Catheter for Labor Epidural Analgesia

Start date: November 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether multiple ports improve the analgesic efficacy of flexible catheters used for the provision of epidural analgesia during the entire continuum of labor and delivery

NCT ID: NCT01846221 Completed - Labor Pain Clinical Trials

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

Start date: July 15, 2014
Phase: Phase 4
Study type: Interventional

Epidural analgesia has proven to be an effective method for severe pain relief associated with labor and delivery. During labor, a low dose continuous infusion of local anesthetic and narcotic will be administered through an epidural catheter. As labor progresses and the baby's head makes it way through the pelvis, breakthrough pain may emerge and often needs further treatment. The investigators provide pain relief by administering analgesics through the epidural catheter. The patients will be randomly assigned to receive one of two medication mixtures believed to be successful in treating this type of pain associated with advanced labor. After this initial treatment, if pain relief is not attained, the patient may receive the other medication as well. The medications used in this study have been used at this institution for some time and have been found to be safe for mother and baby. The opioid (fentanyl) dose is small and only a small fraction will be transmitted to the baby. The other medication (clonidine) better known as a blood pressure medication has also been used for pain relief. Studies and clinical experience have shown that clonidine when given epidurally in the doses used in this study has minimal, if any effect, on the blood pressure of the mother or of the baby. The investigators will record medical and obstetric history and labor progress relevant to the patient. The patient will be asked questions regarding labor pain and side effects before and after the analgesic is administered. The primary objective is to determine which treatment regimen is more successful in abolishing breakthrough pain in advanced labor.

NCT ID: NCT01817829 Completed - Labor Pain Clinical Trials

Oral Paracetamol as Preemptive Analgesia for Labor Pain

Start date: December 2011
Phase: Phase 3
Study type: Interventional

It is a double blinded randomized control trial assessing the use of Oral paracetamol in managing the intrapartum pain.

NCT ID: NCT01810406 Completed - Pregnancy Clinical Trials

Epidural Volume Extension During a Combined Spinal-Epidural Technique for Labor Analgesia.

Start date: March 2013
Phase: N/A
Study type: Interventional

Combined spinal-epidurals (CSE) involve the injection of pain relief medication into the cerebral spinal fluid (CSF) and the insertion of an epidural catheter in the epidural space to continue to give pain relief medication. During a CSE, after injection of the medication in the CSF and before inserting the epidural catheter, if normal saline is injected into the epidural space, there may be an increase in pain relief and an increase in the level of numbness. This injection of saline in the epidural space to increase pain relief and numbness is termed epidural volume extension (EVE). The purpose of this study is to determine if there is a benefit for EVE to improve labor analgesia (pain relief) using CSE in pregnant laboring patients.

NCT ID: NCT01750099 Completed - Labor Pain Clinical Trials

Pain Relief Effects on Length of Labor

Start date: February 2013
Phase: N/A
Study type: Interventional

This study divides patients into two groups when they ask for medicine to help relieve the pain of contractions. One group will be selected to receive an epidural and another group will be selected to receive both a spinal dose and an epidural. The investigators will then measure how long it takes to deliver the baby. The investigators think that the group that has the combination spinal and epidural will have a faster labor.

NCT ID: NCT01709591 Completed - Labor Pain Clinical Trials

Effect of Prenatal Education on Perceptions of Epidural Acceptance

Start date: June 2011
Phase: N/A
Study type: Interventional

The purpose of the study is to determine if targeted prenatal educational program on womens' perceptions of epidural increases the acceptance of intrapartum epidural analgesia relative to the control group.

NCT ID: NCT01687933 Completed - Anxiety Clinical Trials

The Effect of Virtual Reality Glasses on Labor Pain

Start date: February 2011
Phase: Phase 2/Phase 3
Study type: Interventional

There are different medicinal and non medicinal methods to control labor pain. Today, much attention has been on non medicinal methods because of limitations and complications of medical procedures. Virtual reality is a new and promising method of diversion of mind that may have an impact on labor pain. This study was conducted to determine the effect of virtual reality on the first stage of labor pain.

NCT ID: NCT01644838 Completed - Labor Pain Clinical Trials

Effect of Hyoscine and Promethazine on Labor Pain

Start date: August 2010
Phase: Phase 2/Phase 3
Study type: Interventional

It is always considered to shorten the duration of delivery without compromising the mother and fetus by obstetrics. Hyoscine and Promethazine are used widely in hospital and research is very limited, with conflicting results regarding the efficacy of these two drugs. So the investigators decided to compare of effect of hyoscine N-butyl bromide and Promethazine on length of active phase of the first stage of labor.