Accuracy of IVCCI as a Measure of CVP

IVC Collapsibility Index Clinical Trial

Official title:

Accuracy of Inferior Vena Cava Collapsibility Index as a Measure of Central Venous Pressure

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06166875
• Other study ID #: MD186/2023
• Status: Not yet recruiting
• Start date: February 15, 2024
• Est. completion date: May 15, 2025

Study information

• Verified date: December 2023
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The primary aim of the current study is to examine the accuracy of IVCCI for measurement of CVP and to derive equation or formula to predict CVP from IVCCI.

Description:

Hemodynamic monitoring is important in the management of patients in the intensive care unit (ICU) Assessment of the intravascular volume, infusion of fluids or vasoactive drugs and maintenance of an adequate systemic perfusion is essential for reduction of the risk of organ failure and/or mortality.

The use of CVP through central venous catheter is a gold standard method that is extensively used in the ICU as it reflects the filling pressure of the right ventricle (RV) and RV preload.

Central venous cannulation has significant complications such as pneumothorax, hemothorax, arterial puncture, catheter malposition, cardiac arrhythmias, venous embolism, subcutaneous hematoma, and catheter related infection, and it is difficult to use this method in an emergency situation as it requires skilled personnel.

Measurement of IVC index by bedside ultrasound is widely used to assess the intravascular volume in adult patients and has the advantage of being non-invasive, rapid, and reliable for assessing the volume status.

Besides, related measures such as IVC diameter, IVC collapsibility, and IVC to aorta (AO) diameter have been applied clinically to assess the volume status and have been related to CVP.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 160
• Est. completion date: May 15, 2025
• Est. primary completion date: April 15, 2025
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age: =18 years.

• Sex: Both sexes.

• BMI: <35

• Patient in whom central venous cannulation is needed for management.

• Spontaneously breathing patients.

Exclusion Criteria:

• Patients with increased intra abdominal pressure.

• Patients who not able to lie supine.

• Patients on mechanical ventilation.

Related Conditions & MeSH terms

• IVC Collapsibility Index

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The primary outcome of the current study is to examine the accuracy of IVCCI for measurement of CVP and to derive equation or formula to predict CVP from IVCCI.		18 months