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Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China — TTT-AIS CHINA  

Ischemic Stroke Clinical Trial

Official title:
Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China a Real-world, Multicenter, Retrospective, Controlled Study

Clinical Trial Summary

The objective of the study is to investigate the effectiveness and safety of rhTNK-tPA in acute ischemic stroke patients within 4.5 hours of symptom onset in a real-world clinical setting.

Clinical Trial Description

Recombinant human tenecteplase tissue-type plasminogen activator (rhTNK-tPA) has the logistic advantage of a single bolus infusion over recombinant tissue plasminogen activator (rt-PA) which needs a 1-hour infusion. The non-inferiority of rhTNK-tPA compared to rt-PA was proved by two recent randomized controlled clinical trials but the evidence is lacking regarding the real-world effectiveness and safety of rhTNK-tPA. This is a multi-center, observational, retrospective study that enrolled acute ischemic stroke patients treated with rhTNK-tPA thrombolysis in China. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06078995
Study type Observational
Source Huashan Hospital
Contact Qiang Dong, M.D. Ph.D.
Phone 86-021-52887142
Email qiang_dong163@163.com
Status Recruiting
Phase
Start date April 2, 2023
Completion date May 1, 2024
View Details
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