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Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke — EXTEND-IA TNK  

Ischemic Stroke Clinical Trial

Official title:
Extending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial Using Intravenous Tenecteplase

Clinical Trial Summary

Patients presenting to the emergency department with acute ischemic stroke, who are are eligible for standard intravenous tPA therapy within 4.5 hours of stroke onset will be assessed for major vessel occlusion to determine their eligibility for randomization into the trial. If the patient gives informed consent they will be randomised 50:50 using central computerised allocation to intravenous alteplase or tenecteplase before all participants undergo intra-arterial clot retrieval. The trial is prospective, randomised, open-label, blinded endpoint (PROBE) design.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02388061
Study type Interventional
Source Neuroscience Trials Australia
Contact
Status Completed
Phase Phase 2
Start date March 23, 2015
Completion date February 2018
View Details
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