Iron-deficiency Clinical Trial
Official title:
ProPBM : A Randomised Control Trial Comparing a Modified Patient Blood Management Protocol Against Standard Care for Patients Undergoing Major Surgery
The introduction of a modified perioperative patient blood management protocol with intravenous iron intervention for iron deficiency anaemic patients would reduce the need for allogenic blood transfusion and reduce perioperative morbidity and mortality.
Patient blood management (PBM), refers to "the timely application of evidence based medical
and surgical concepts designed to maintain haemoglobin concentration, optimise haemostasis
and minimize blood loss in an effort to improve patient outcome.
PBM relies on three corresponding aspects:
1. Optimising haemopoiesis,
2. Minimising bleeding and blood loss
3. Harnessing and optimising physiological tolerance of anaemia.
Therefore, this randomised control trial aims to study the effect of applying a modified
patient blood management protocol on the perioperative allogenic blood transfusion incidence,
mortality and morbidity in patients undergoing major surgery in gynaecology, intraabdominal
surgery and orthopaedics comparing with current practice.
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