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Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial — DREAM-PRIDE  

Stroke Clinical Trial

Official title:
Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial: a Prospective, Randomized, Open-labelled, Blinded End-point Trial (DREAM-PRIDE)

Clinical Trial Summary

The aim of DREAM-PRIDE is to evaluate whether implantation of drug-eluting stent (DES) combined with aggressive medical treatment is more efficacious in prevention of 1-year stroke recurrence than standard medical treatment alone for symptomatic intracranial atherosclerotic disease.

Clinical Trial Description

This trial is a prospective, multi-center, 1:1 randomized using drug-eluting (Sirolimus) stent combined with aggressive medical treatment versus standard medical treatment to treat symptomatic intracranial atherosclerotic disease. Primary efficacy endpoints (any of the following): 1) any stroke or death within 30 days after enrollment, 2) any stroke or death within 30 days after a revascularization procedure of the qualifying lesion during follow-up, 3) ischemic stroke in the territory of the qualifying artery beyond 30 days to 1 year. ;

Study Design

Related Conditions & MeSH terms

  • Intracranial Atherosclerotic Disease
  • Stroke
Clinical Trial Details
NCT number NCT04948749
Study type Interventional
Source Beijing Tiantan Hospital
Contact Ning Ma, MD
Phone 13581889908
Email maning_03@hotmail.com
Status Recruiting
Phase N/A
Start date July 2, 2021
Completion date July 2025
View Details
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