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Influenza, Human clinical trials

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NCT ID: NCT03448705 Completed - Human Influenza Clinical Trials

Safety of 4Fluart ID Suspension for Injection in Adult Subjects

Start date: January 31, 2018
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the safe usability of the study drugs, i.e. 4Fluart ID 1 µg haemagglutinin (HA)/0.1 ml QIV and 4Fluart ID 2 µg haemagglutinin (HA)/0.1 ml QIV in terms of safety concerns emerged. The secondary objective of the study is to further assess safety in terms of safety parameters, as well as to assess the immunogenicity of 4Fluart ID 1 µg haemagglutinin (HA)/0.1 ml QIV and 4Fluart ID 2 µg haemagglutinin (HA)/0.1 ml QIV in terms of immunogenicity parameters.

NCT ID: NCT03445468 Completed - Influenza, Human Clinical Trials

Immunogenicity and Safety for 'IL-YANG Quadrivalent Influenza Vaccine' in Healthy Korean Children and Adolescents

Start date: September 20, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity and safety of 'IL-YANG Quadrivalent Seasonal Influenza Vaccine' in healthy Korean children and adolescents.

NCT ID: NCT03445117 Completed - Clinical trials for Immunization Programs

Increasing the Uptake of Influenza and Pneumococcal Vaccines Among High-Risk Adult Patients Through GP Clinics

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Pneumonia and influenza are among the top causes of hospitalisation and death in the elderly. While vaccinations are recommended against these diseases, a large proportion of elderly in the community remain unvaccinated, with approximately only 10% vaccinated for either disease. In this study, the investigators aim to implement an intervention package within GP clinics to increase influenza and pneumococcal vaccination rates, especially among elderly patients with chronic diseases.

NCT ID: NCT03442582 Completed - Pregnancy Clinical Trials

Afluria Pregnancy Registry

Start date: September 8, 2017
Phase:
Study type: Observational

The study is a population based prospective cohort study designed to collect data on pregnancy outcomes and events of interest among women immunized with Afluria during pregnancy.

NCT ID: NCT03441373 Completed - Influenza Clinical Trials

XC8 in the Treatment of Patients With Acute Respiratory Viral Infection

Start date: February 3, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

A multicenter double-blind, randomized, placebo-controlled, parallel-group comparative Phase II / III clinical study to assess safety, tolerability, efficacy and optimal dose ranging of XC8 vs. placebo in patients with uncomplicated influenza or other ARVI during a 5-day treatment. The primary objective of the study was to demonstrate the difference in time before the onset of a sustained improvement in clinical symptoms according to the Severity Rating Scale for ARVI, and to determine the optimal dose of XC8 in the treatment of influenza and other ARVI.

NCT ID: NCT03438487 Completed - Pregnancy Clinical Trials

Flucelvax (TIVc or QIVc) Pregnancy Registry

Start date: September 1, 2017
Phase:
Study type: Observational

The study is a population based prospective cohort study designed to collect data on pregnancy outcomes and events of interest among women immunized with the TIVc or QIVc vaccine during pregnancy.

NCT ID: NCT03430089 Completed - Influenza Clinical Trials

Safety of a Single Dose or Two Doses of Shenzhen Quadrivalent Influenza Vaccine

Start date: February 22, 2019
Phase: Phase 1
Study type: Interventional

This phase I-like, open-label, monocenter, descriptive, single-arm clinical safety study will investigate the Shenzhen quadrivalent influenza vaccine (Shz QIV) in 100 participants aged 6 months and older in China. Participants aged 9 years or more will receive a single dose of Shz QIV, and participants aged 6 months to 8 years will receive two doses of Shz QIV administered 28 days apart.

NCT ID: NCT03417869 Completed - Clinical trials for Influenza A, Influenza B

QuickVue Influenza A + B Test Field Study

QuickVue Flu
Start date: February 16, 2017
Phase:
Study type: Observational

Demonstrate improved clinical performance of visually read QuickVue Influenza A+B test.

NCT ID: NCT03413228 Not yet recruiting - Influenza Clinical Trials

Nosocomial Influenza Surveillance 2018 - 2022

NOSOGRIPPE
Start date: February 2018
Phase: N/A
Study type: Observational

Hospital-acquired influenza is associated with significant morbidity and mortality in hospitalized patients notably elderly patients. Furthermore, it is also associated with a large economic impact for the hospitals. The transmission of influenza has been mostly reported in pediatric and long-stay units. The chains of transmission of influenza in acute-stay units have to be describe in order to prevent and control potential outbreaks. Furthermore, to know clinical symptoms seems to be important in order to identify potential sources of virus as soon as possible and to set up appropriate hygiene prevention measures. Moreover, the definition of the hospital-acquired influenza has to be harmonized for all over the studies, especially concerning the delay between the admission in the hospital and the symptoms onset. The aim of this study is to describe the hospital-acquired influenza in a french university hospital of around 800 beds

NCT ID: NCT03410862 Completed - Influenza, Human Clinical Trials

Evaluating The Safety And Clinical Efficacy Of Elderberry Extract In Patients With Influenza

Start date: January 29, 2018
Phase: Phase 4
Study type: Interventional

This research is being done to determine if an extract of cooked elderberries will help decrease the duration and severity of influenza symptoms in patients with confirmed influenza. Involvement in this study requires an initial patient screening at the time of their Emergency Department visit in order to confirm eligibility for the study. Once patients have been consented and enrolled as a participant, they will be randomized to take by mouth either Elderberry Extract or a placebo (a similar appearing and tasting liquid without elderberry) for a duration of 5 days. Study information regarding medication adherence, body temperature, symptoms, severity of symptoms, and any possible side effects will be collected from daily phone surveys conducted by the study coordinator. Participation in the study will end after at least 5 days once the patient has not had a temperature above 100°F and has had no influenza symptoms for at least 24 hours, or after 21 days in the study, whichever occurs first.