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Influenza, Human clinical trials

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NCT ID: NCT05157425 Completed - Influenza Vaccine Clinical Trials

Effect of a Multi-strain Probiotic Formulation on Immune Response to Influenza Vaccination

FLUVAC21
Start date: October 26, 2021
Phase: N/A
Study type: Interventional

Randomized clinical trial to determine whether a probiotic formulation containing 4 probiotic strains which belong to Lactiplantibacillus plantarum and Pediococcus acidilactici species can boost the immune response to influenza vaccination evaluated at 4 weeks in a population between 50 and 80 years of age. Secondary outcomes comprise evaluation of immune response at 8 weeks after vaccination, percentage of patients with seroconversion, incidence and duration of influenza-like infections and respiratory infections throughout a 4-month period and safety.

NCT ID: NCT05155319 Completed - Human Influenza Clinical Trials

Universal Influenza A Vaccine in Healthy Adults

EBS-UFV-001
Start date: December 1, 2021
Phase: Phase 1
Study type: Interventional

The goal of this Phase 1, single- center, randomized, double blind, placebo-controlled dose-escalation study is to evaluate the safety, tolerability and immunogenicity of UFluA vaccine candidate at two dose levels and two schedules in healthy adult (18-45-year-old, inclusive) male and non-pregnant female subjects.

NCT ID: NCT05152017 Completed - Influenza Clinical Trials

The Objectives of This Study Are Study the Safety, Reactogenicity and Obtain Preliminary Data on the Immunogenicity of Flu-M Quadro, 4-valent Inactivated Split Influenza Vaccine, in Healthy Volunteers

Start date: November 16, 2019
Phase: Phase 1
Study type: Interventional

The study the safety, reactogenicity and obtain preliminary data on the immunogenicity of Flu-M Quadro, 4-valent inactivated split influenza vaccine, in healthy volunteers

NCT ID: NCT05144945 Completed - Clinical trials for Influenza (Healthy Volunteers)

Study Describing the Immunogenicity and Safety of Quadrivalent Recombinant Influenza Vaccine (RIV4) Versus a Licensed Quadrivalent-inactivated Influenza Vaccine (IIV4) (Fluarix® Quadrivalent) in Participants 18 Years of Age and Older in South Korea

Start date: December 7, 2021
Phase: Phase 3
Study type: Interventional

- To describe the immune response induced by quadrivalent recombinant influenza vaccine (RIV4) and Quadrivalent-inactivated Influenza Vaccine (IIV4) in 18-49 and greater than or equal to (>=) 50 years of age participants by hemagglutination inhibition (HAI) measurement method. - To describe the safety profile of all participants in RIV4 and IIV4 groups.

NCT ID: NCT05138705 Completed - Influenza, Human Clinical Trials

Clinical Trial of Quadrivalent Influenza Virus Split Vaccine in Population Aged 3-8 Years

Start date: December 14, 2021
Phase: Phase 4
Study type: Interventional

To evaluate the safety and immunogenicity of quadrivalent influenza virus split vaccine in healthy population aged 3-8 years following different immunization procedures.

NCT ID: NCT05126979 Completed - Influenza Clinical Trials

The Objectives of This Study Are Study of the Reactogenicity, Safety and Immunogenicity of Flu-M Inactivated Split Influenza Vaccine in Volunteers Aged 18-60 Years

Start date: March 9, 2016
Phase: Phase 1
Study type: Interventional

Study of the Reactogenicity, Safety and Immunogenicity of Flu-M Inactivated Split Influenza Vaccine in Volunteers Aged 18-60 Years

NCT ID: NCT05107375 Completed - Clinical trials for Coronavirus Disease 2019

Clinical Study of Recombinant Novel Coronavirus(COVID-19) Vaccine (CHO Cell) Combined With Influenza Vaccine

Start date: September 3, 2021
Phase: Phase 3
Study type: Interventional

Popular topic:Clinical study of recombinant Novel Coronavirus vaccine (CHO cell) combined with influenza vaccine. Research purpose:Main purpose:To evaluate the immunogenicity of recombinant Novel Coronavirus vaccine (CHO cells) combined with influenza vaccine in people aged 18 years and over. Secondary purpose:To evaluate the safety of recombinant Novel Coronavirus vaccine (CHO cells) combined with influenza vaccine in people aged 18 years and over. Overall design:An open experimental design was adopted in this study, and 300 subjects were planned to be enrolled. To evaluate the immunogenicity and safety of recombinant Novel Coronavirus vaccine (CHO cells) in combination with influenza vaccine. Study population:The study involved people 18 years of age and older. Test groups:A total of 300 cases were enrolled. 240 patients in 18-59 years old group, 60 patients in ≥60 years old group. There were 150 cases in group A, 120 cases in 18-59 years old group, and 30 cases in ≥60 years old group. There were 150 cases in group B, 120 cases in 18-59 years old group and 30 cases in ≥60 years old group.

NCT ID: NCT05095545 Completed - Influenza Clinical Trials

Dose Range Study to Evaluate the Efficacy and Safety of AV5080 in Patients With Influenza

Start date: November 13, 2017
Phase: Phase 2
Study type: Interventional

Assessment of the effect reached with the different doses of AV5080 on the duration and severity of influenza symptoms based on the incidence of their resolution within 96 hours from study treatment initiation compared to Placebo. The absence of influenza symptoms or their reduction to mild severity for at least 24 hours indicates the resolution of influenza.

NCT ID: NCT05089123 Completed - Influenza Clinical Trials

The Objectives of This Study Are Study the Immunogenicity and Safety of the Flu-M [Inactivated Split Influenza Vaccine], vs. the Ultrix® Inactivated Split Influenza Vaccine, in Volunteers Who Are Over 60 Years Old

Start date: March 3, 2020
Phase: Phase 3
Study type: Interventional

This trial by its design was a prospective, multicenter, double blind, randomized comparative clinical trial of the IIIb-IV phase which was carried out in parallel groups of volunteers over the age of 60

NCT ID: NCT05087355 Completed - Influenza Clinical Trials

Health Status Prior and Post Infection With Influenza or COVID 19: a Population Based Retrospective Analysis of 2016-2021

Start date: January 1, 2016
Phase:
Study type: Observational

The overall project aim is to study outcomes after COVID-19 and influenza hospitalisation from 2016 - 2021 by retrieving data from the main social security carriers in Austria for the years 2010-2018