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Hypothermia clinical trials

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NCT ID: NCT03157609 Completed - Children Clinical Trials

Can the SpotOn™ Zero-Heat-Flux-Thermometry Sensor Accurately Measure Core Temperature in Children?

Start date: November 15, 2017
Phase: N/A
Study type: Interventional

The present study aims to assess the accuracy of the SpotOn™ Zero-heat-flux-thermometry sensor in measuring core temperature in the paediatric population in the perioperative period.

NCT ID: NCT03150953 Completed - Clinical trials for Congenital Heart Disease

Evaluation of a Novel Patient Warming System During MRI

Start date: May 26, 2016
Phase: N/A
Study type: Interventional

Patients under deep sedation and general anesthesia lose heat to their surrounding environment. Hypothermia after anesthesia is associated with worse patient outcomes, including increased number of infections and cardiovascular complications. Cardiac MRI scans performed for patients who require general anesthesia can cause a loss of body heat. Several mechanisms exist for reducing hypothermia under anesthesia including forced air warmers, fluid warmers, radiant warmers, and chemical warmers. Unfortunately, there are no MRI-compatible systems which allow patient warming and prevention of hypothermia in anesthetized patient in the MRI-scanner. This study is testing a non-invasive device that warms patients under clinically indicated general anesthesia in the MRI scanner. This device will keep in the heat made by the MRI scanner.

NCT ID: NCT03141723 Completed - Preterm Infant Clinical Trials

Kangaroo Mother Care With Plastic Bag (Trials 2A & 2B)

Start date: May 19, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the combination of Kangaroo Mother Care (KMC) as continuously as possible together with the use of a plastic bag in combination with routine World Health Organization (WHO) thermoregulation care reduces the incidence of moderate (32-36° C) or severe (<32.0° C) hypothermia in term infants ≥ 37 0/7 weeks of gestational age (GA) when compared to KMC as continuously as possible together with routine WHO thermoregulation care.

NCT ID: NCT03129620 Completed - Hypothermia Clinical Trials

Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy

Start date: March 2013
Phase: N/A
Study type: Observational

Controlled Hypothermia has become the standard of care for neonates with moderate to severe HIE. Ampicillin and aminoglycosides are drugs that are universally used for the treatment of suspected neonatal sepsis, which may or may not be responsible for the etiology of HIE. Currently, medication dosage regimens are not altered in the setting of CH. A better understanding of the effects of our interventions on this unique population may help us tailor our therapy to the specific circumstances of the patient

NCT ID: NCT03122665 Completed - Hypothermia Clinical Trials

Effectiveness of Nefopam for Thermoregulation During Surgery

Start date: August 2004
Phase: N/A
Study type: Interventional

Nefopam may help blunt thermoregulatory defenses, thus facilitating induction of therapeutic hypothermia

NCT ID: NCT03112317 Completed - Clinical trials for Surgical Site Infection

Mild Hypothermia Influence on Patient Outcome in Major Abdominal Surgery

Start date: May 30, 2019
Phase:
Study type: Observational

This study investigate associations between mild hypothermia (patients' core temperature ≤ 36.0 degrees Celsius) and intra-operative blood loss and surgical site infections (SSI) in patients undergoing major abdominal surgery.

NCT ID: NCT03111875 Completed - Clinical trials for Surgery--Complications

Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery

PROTECT
Start date: March 27, 2017
Phase: N/A
Study type: Interventional

We propose to test the hypothesis that aggressive warming reduces the incidence of major cardiovascular complications, compared to routine care. Half of the participants will be randomly assigned to routine care (core temperature ≈35.5°C), while the other half will receive aggressive warming (>37°C core temperature) in a multi-center trial.

NCT ID: NCT03098706 Completed - Critical Illness Clinical Trials

Therapeutic Hypothermia in "Expanded Criteria" Brain-dead Donors and Kidney-graft Function

HYPOREME
Start date: November 8, 2017
Phase: N/A
Study type: Interventional

Each year, only one third of patients registered on the waiting list receive a kidney transplant. Numerous paths are being explored with the aim of reversing this shortage. The first is to increase the number of organs by developing harvesting from donors in a state of brain-death (BD) termed "expanded criteria donors" or from patients deceased from circulatory arrest. Another fundamental factor is to insure the success of the transplant by limiting the dysfunction of donor kidneys, marked by a delayed graft function (DFG). The development of techniques to insure correct perfusion of harvested organs, and the optimization of reanimation and intensive care of brain-dead donors constitute important factors in DGF reduction. Therapeutic Hypothermia could to be an attractive care strategy for BD patients.

NCT ID: NCT03081000 Completed - Clinical trials for Disturbance; Temperature Regulation

Perioperative Hypothermia: A Multi-center Study of Incidence, Risk Factors and Preventive Measures.

Start date: October 2015
Phase: N/A
Study type: Observational

Aims:- Primary: To identify the incidence of intra-operative and post-operative hypothermia Secondary: To identify factors contributing to peri-operative hypothermia. To identify current anaesthetic practice in peri-operative temperature monitoring, use of active/warming measures by anaesthetists in various hospitals. To increase awareness of the problem of IPH and guidelines available.

NCT ID: NCT03079284 Completed - Clinical trials for Hypoxic-Ischemic Encephalopathy

Holding, Stress, and Bonding During Therapeutic Hypothermia

Start date: March 20, 2017
Phase: N/A
Study type: Interventional

Ten infants undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy will be enrolled in a new protocol that will allow mothers to hold their infants during the hypothermia treatment period. This is a safety study that will assess whether or not there is an increase in adverse event frequency in infants that are held during hypothermia. Parents and NICU nurses will be given a questionnaire after holding is complete investigating their feelings on maternal-infant bonding and safety of the holding protocol.