Clinical Trials Logo

Clinical Trial Summary

NHP referred to our outpatient clinic will be enrolled (150 newly recruited) in acute saline test for phenotype characterisation of PNat relationship(7). For each patient we will collect urine and blood samples for standard clinical biochemistry, including electrolytes, creatinine, EO, aldosterone, plasma renin activity, urinary uromodulin (ELISA), urinary and serum uric acid and blood samples for genetic test.


Clinical Trial Description

Acute salt load test: after the equilibration period and achievement of a steady state, a constant-rate i.v. infusion of 2 L of 0.9% NaCl was carried out in 2 hours. BP (mean of 3 measurements taken 3 minutes apart) was measured every 30 minutes during the 2 hours of loading and 3 times at 3-min intervals at the end of the infusion. These last 3 BP values were averaged and used in the analysis. The results of these tests will be added to an already collected database of salt load test collected in the previous studies (already published) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04625569
Study type Observational
Source Ospedale San Raffaele
Contact Chiara Lanzani, doctor
Phone 0206433891
Email lanzani.chiara@hsr.it
Status Recruiting
Phase
Start date July 8, 2019
Completion date November 8, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT05020574 - Microbiome and Association With Implant Infections Phase 2
Recruiting NCT06057181 - Helix Research Network
Recruiting NCT04390269 - Immunogenetics Predictors With COVID-19
Recruiting NCT04427163 - Assesment of Multiomics Profiles in Health and Disease.
Completed NCT03597659 - PheWAS of a Polygenic Predictor of Thyroid Function
Active, not recruiting NCT04634032 - Gene Expression and DNA Variation Analysis of Sacs to Identify the Pathophysiology of Indirect Inguinal Hernia
Completed NCT04145817 - Breast Cancer Risk After Diagnostic Gene Sequencing N/A
Recruiting NCT04600544 - Russian Disc Degeneration Study
Not yet recruiting NCT04788927 - Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Not yet recruiting NCT03234140 - Constitutional Genetics in Follicular Lymphoma N/A
Completed NCT01973075 - Genetic Etiology in Premature Ovarian Insufficiency N/A
Completed NCT00555503 - Registry of Mastectomy for Breast Cancer Risk Reduction N/A
Active, not recruiting NCT05524909 - Full-scale Intervention Study: Genetic Risk Communication and Wearables N/A
Suspended NCT04151368 - Surgical and Patient Reported Outcomes of Robotic Nipple-Sparing Mastectomy N/A
Active, not recruiting NCT02422511 - Genomic Sequencing for Childhood Risk and Newborn Illness N/A
Completed NCT00677495 - Gluten-free Diet in Gluten-genetically Predisposed Subjects N/A
Recruiting NCT05759143 - Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing N/A
Enrolling by invitation NCT05721326 - Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition N/A
Active, not recruiting NCT05685810 - Genetic Determinants of Kidney Disease in People of African Ancestry With HIV
Recruiting NCT04903782 - Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer