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Pharmacokinetics of BIA 5-453 and Its Metabolites

Hypertension Clinical Trial

Official title:
Single-dose and Steady-state Pharmacokinetics of BIA 5-453 and Its Metabolites in Healthy Male Elderly Subjects Compared With Those in Healthy Male Young Subjects

Clinical Trial Summary

The purpose of this study was to assess the effects of age on the pharmacokinetic (PK) profile of BIA 5-453 and its metabolites.

Clinical Trial Description

Single-centre, open-label, parallel group, non-randomised study in 12 healthy elderly and 12 healthy younger male subjects, who participated in 2 consecutive phases:

Phase A: a single-dose phase (including a wash out period); Phase B: a multiple-dose phase during 7 days (steady state). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03090724
Study type Interventional
Source Bial - Portela C S.A.
Contact
Status Completed
Phase Phase 1
Start date June 13, 2008
Completion date August 12, 2008
View Details
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