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Hypersensitivity clinical trials

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NCT ID: NCT02773758 Completed - Dentin Sensitivity Clinical Trials

Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity

Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

This will be a single centre, two week, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), controlled study, in participant with at least two sensitive teeth that meet the study criteria at the Screening and Baseline visits. The study will be conducted in participants in good general health, with pre-existing self-reported and clinically diagnosed tooth sensitivity at screening.

NCT ID: NCT02767869 Completed - Clinical trials for Metabolic Syndrome X

Effect of Banaba (Lagerstroemia Speciosa) on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity

Start date: January 2015
Phase: Phase 2
Study type: Interventional

The Metabolic Syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers the disease. Banaba has shown evidence that has on metabolic syndrome, insulin sensitivity and insulin secretion. The investigators hypothesis was that the the administration of resveratrol modifies the metabolic syndrome, insulin sensitivity and insulin secretion.

NCT ID: NCT02766127 Completed - Xerostomia Clinical Trials

Effect of a Self-adhering Material in Dental Hypersensitivity

Start date: March 2012
Phase: N/A
Study type: Interventional

Aim: To compare the desensitizing capacity of Vertise Flow™ (VF), a new self adhering material, in the treatment of dentine hypersensitivity (DH) in patients who are xerostomic due to radiotherapy for head and neck cancer. Methods: A total of 17 patients were selected for the study. The study was conducted as a split-mouth randomized clinical trial comparing: 1) VF 2) Universal Dentin Sealant (UDS), 3) Clearfil Protect Bond (CPB) and 4) Flor-Opal® Varnish (FOV). Basal and stimulated salivary flow was recorded for each patient according to the method described by Sreebny. The pain experience was generated by a cold stimulus directly to a sensitive tooth surface and assessed using the Visual Analogue Scale (VAS). The response was recorded before the application of the materials (PRE-1), immediately after (POST-1), at 1-week (POST-2), 4-weeks (POST-3) and 12-week controls (POST-4).

NCT ID: NCT02753075 Completed - Dentin Sensitivity Clinical Trials

A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.

Start date: September 8, 2015
Phase: N/A
Study type: Interventional

This study will investigate the longitudinal efficacy of two experimental oral rinses, one containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX) /0 Parts per Million (ppm fluoride) and the other 2.0% w/w KOX /45ppm fluoride, for the relief of dentinal hypersensitivity (DH), compared to a placebo oral rinse, when used as an adjunct to twice daily brushing with a standard fluoride toothpaste.

NCT ID: NCT02752958 Completed - Dentin Sensitivity Clinical Trials

Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health

Start date: May 23, 2016
Phase: N/A
Study type: Interventional

This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers. Changes in oral health related quality of life will be monitored using the Dentine Hypersensitivity Experience Questionnaire (DHEQ). The study will be conducted in participants in good general health, with pre-existing self-reported and clinically diagnosed tooth sensitivity at screening.

NCT ID: NCT02751450 Completed - Dentin Sensitivity Clinical Trials

The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity(DH)

Start date: February 2016
Phase: N/A
Study type: Interventional

This single centre, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a standard fluoride dentifrice.

NCT ID: NCT02745613 Completed - Clinical trials for Insulin Sensitivity/Resistance

Type 2 Diabetes Affect Exercise Induced Improvement in Insulin Sensitivity

HIT
Start date: April 2016
Phase: N/A
Study type: Interventional

This study investigates weather a family history of type 2 diabetes affects exercise induced improvements in insulin sensitivity in the hispanic population

NCT ID: NCT02738060 Completed - Cow's Milk Allergy Clinical Trials

The Effect of Baked Milk on Cow's Milk Allergy

Start date: September 2015
Phase: Phase 2
Study type: Interventional

To investigate the effect of baked milk in immunotherapy of cow's milk allergy.

NCT ID: NCT02731833 Completed - Dentin Sensitivity Clinical Trials

Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity

Start date: April 2016
Phase: Phase 4
Study type: Interventional

This single centre, comparative design study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a standard fluoride dentifrice

NCT ID: NCT02711163 Completed - Cow Milk Allergy Clinical Trials

Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula

ALYCE
Start date: April 2016
Phase: Phase 3
Study type: Interventional

The aim of this study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula, in infants with confirmed cow's milk protein allergy assessed through a double blind placebo controlled food challenge, followed by a 3-month open feeding period.