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Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study)

Hyperlipidemia Clinical Trial

Official title:
Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study)

Clinical Trial Summary

To evaluate the primary preventive effect of low-dose pravastatin against coronary heart disease (CHD) in Japanese hypercholesterolemic patients.

Clinical Trial Description

MEGA Study is the first prospective, randomized, controlled trial conducted in Japan to evaluate the primary preventive effect of pravastatin against CHD in daily clinical practice. Because the dose of pravastatin used in the MEGA Study was 10–20 mg/day, which is consistent with the approved doses in Japan and lower than the doses used in previous large-scale clinical trials. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00211705
Study type Interventional
Source Mitsukoshi Health and Welfare Foundation
Contact
Status Completed
Phase Phase 4
Start date February 1994
Completion date March 2004
View Details
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