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Hydrocephalus clinical trials

View clinical trials related to Hydrocephalus.

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NCT ID: NCT04496414 Completed - Hydrocephalus Clinical Trials

Bactiseal Catheter Safety Registry in China

Start date: September 1, 2020
Phase:
Study type: Observational [Patient Registry]

Research Purpose: This study aimed to continue to evaluate safety information from subjects implanted with a catheter (trade name: Bactiseal) produced by Codman & Shurtleff, Inc. of the United States. Device safety would be assessed based on all the adverse events that occurred within one year after the subjects implanted the catheter.

NCT ID: NCT04471740 Recruiting - Sleep Apnea Clinical Trials

Normal Pressure Hydrocephalus and Sleep Apnea

NPH/OSA
Start date: July 2, 2020
Phase: N/A
Study type: Interventional

Normal-pressure hydrocephalus is associated with increases in the intracranial pressure during the night sleep. Sleep apnea also increases the intracranial pressure during the apneic spells. When patients are operated the distal part of the shunt is inserted inside the abdominal cavity, which pressure also increases during the sleep apnea episodes. this is particularly important considering that the recumbent position used to sleep further increases the intraabdominal pressure and that impairs the CSF drainage through the shunt system. The purpose of this study is to analyze the intracranial and intraabdominal pressures during the sleep, particularly during the sleep apnea episodes to see which shunt should be used, to which cavity should be drained (peritoneum or heart) and if correcting the sleep apnea has some positive result on the hydrocephalus symptoms.

NCT ID: NCT04450797 Recruiting - Hydrocephalus Clinical Trials

Intraoperative Ultrasound Guided Compared to Stereotactic Navigated Ventriculoperitoneal Shunt Placement

NaVPS
Start date: February 26, 2020
Phase: N/A
Study type: Interventional

This study is to prospectively compare Ultrasound guided (US-G) Ventriculoperitoneal Shunt (VPS) placement to stereotactic navigation in a randomized controlled fashion with the surgical intervention time as primary outcome. All patients entering the University Hospital of Basel for elective or emergent VPS surgery will be randomized in 1:1 fashion to one of the study groups at admission or the day before the operation.

NCT ID: NCT04436068 Recruiting - Hydrocephalus Clinical Trials

Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging

Start date: June 28, 2019
Phase: N/A
Study type: Interventional

Participants with known or suspected hydrocephalus will receive brain scans using the Hyperfine, low field strength, portable, magnetic resonance imaging (MRI) system in addition to their scheduled outpatient standard of care clinical computed tomography (CT) or MRI scan. The purpose of this pilot study is to evaluate the feasibility and acceptability of using the Hyperfine system in an outpatient setting and to compare its diagnostic performance to standard clinical imaging. Outpatients with other known or suspected neurological disorders or conditions prompting routine clinical brain imaging with MRI or CT will also be enrolled and the diagnostic performance of low field scans compared to that of the same day standard of care clinical imaging.

NCT ID: NCT04434053 Recruiting - Clinical trials for Normal Pressure Hydrocephalus

Adjustable Gravitational vs. Adjustable Differential Pressure Valves in iNPH

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The goal of the study is to verify theoretical benefit of ventriculoperitoneal shunting with MIETHKE M.blue® valve in patients with iNPH. The study is designed to assess walking and balance, urinary function, cognitive performance and quality of life before and after shunting and compare the results between the patients with MIETHKE M.blue® and MIETHKE proGAV 2.0® (with SA 2.0®) valves.

NCT ID: NCT04363658 Recruiting - Hydrocephalus Clinical Trials

Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology

Start date: May 10, 2020
Phase:
Study type: Observational

The symptoms of hydrocephalus containing consciousness condition with muscle tone in some patients will be relieved, after the cerebrospinal fluid release test is carried out. Neuroelectrophysiology in patients with disorders of consciousness of post-traumatic hydrocephalus (PTH) can establish the association with consciousness and muscle tone to a certain extent, and predict the shunt effect of PTH with disorders of consciousness.

NCT ID: NCT04309487 Recruiting - Clinical trials for Hydrocephalus, Normal Pressure

Diagnostic Accuracy of ShuntCheck Compared to Radionuclide Shunt: Patency in Patients With Normal Pressure Hydrocephalus

Start date: January 24, 2020
Phase:
Study type: Observational

The purpose of this study is to assess the diagnostic accuracy of ShuntCheck compared with radionuclide shunt patency testing (SPS) to detect CSF shunt flow of NPH patients with suspected shunt obstruction.

NCT ID: NCT04285489 Completed - Hydrocephalus Clinical Trials

A Study on the Safety of Hakim Programmable Shunt System

Start date: May 2, 2020
Phase:
Study type: Observational

This study aimed to collect safety information from subjects implanted with a shunt system (trade name: Hakim Shunt Programmable System) produced by Codman & Shurtleff, Inc. of the United States. Device safety would be assessed based on all the adverse events that occurred within one year after the subjects implanted the catheter.

NCT ID: NCT04229693 Recruiting - Clinical trials for Hydrocephalus in Infants

Cerebrospinal Fluid Proteom in Dependence of Intranasal Breast Milk

NAMU
Start date: February 7, 2020
Phase:
Study type: Observational

Investigation of the cerebrospinal fluid proteom in preterm infants with posthemorrhagic hydrocephalus in our neonatology center with analysis for modulation of proteom in dependence of breastmilk feeding and way of application such as via gavage tube, oral or nasal application.

NCT ID: NCT04207229 Completed - Hydrocephalus Clinical Trials

CERTAS Programmable Valve Registry

CERTAS
Start date: November 21, 2019
Phase:
Study type: Observational [Patient Registry]

Post-Market Clinical Follow-up Registry of Patients with CODMAN CERTAS Plus Programmable Valves.