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Early Administration of Romidepsin and 3BNC117 in Treatment-naïve HIV Patients Starting ART — eCLEAR  

Hiv Clinical Trial

Official title:
Early Administration of Latency Reversing Therapy and Broadly Neutralizing Antibodies to Limit the Establishment of the HIV-1 Reservoir During Initiation of Antiretroviral Treatment - a Randomized Controlled Trial

Clinical Trial Summary

To evaluate the effect of early viral reactivation by latency reversing agents (LRA) and/or administration of potent broadly neutralizing antibodies (bNAb) on the size of the latent HIV-1 reservoir in treatment naïve HIV-1 patients initiating antiretroviral therapy (ART)

Clinical Trial Description

The study will be conducted among ART naïve HIV-1-infected patients. Subjects will continue ART while receiving LRA romidepsin and/or bNAb 3BNC117. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03041012
Study type Interventional
Source University of Aarhus
Contact
Status Active, not recruiting
Phase Phase 2
Start date January 20, 2017
Completion date December 30, 2021
View Details
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