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Biomarkers for Muscle Function and Aging in Chronic HIV Infection — MATCH  

HIV Clinical Trial

Official title:
Biomarkers for Muscle Function and Aging in Chronic HIV Infection

Clinical Trial Summary

MATCH is an observation study of HIV-infected adults on effective antiretroviral therapy (ART) and demographically matched uninfected adults to evaluate muscle and aging.

Clinical Trial Description

MATCH is a non-randomized observational longitudinal study. We will recruit HIV infected adults (50 to 65 years old) and demographically matched uninfected control subjects to be followed for 4 years over the course of a 5 year study. The targeted age range of 50-65 is chosen to evaluate aging HIV infected individuals at risk for early frailty in the United States. All subjects will undergo blood draws and physical function assessment, and a subset will undergo a CT scan of muscle and will have a muscle biopsy taken.

A substudy will be performed on a subgroup of HIV-infected and HIV-uninfected men from the main cohort to measure daily physical activity by using an activity tracker. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03011957
Study type Observational
Source Brigham and Women's Hospital
Contact
Status Active, not recruiting
Phase N/A
Start date February 2015
Completion date February 2020
View Details
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