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Hernia clinical trials

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NCT ID: NCT00535990 Completed - Colorectal Cancer Clinical Trials

Minimally Invasive Surgery (MIS) Database for the Purpose of Research

Start date: September 2007
Phase:
Study type: Observational

The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD. The hope is that collection of this information will give physicians a better knowledge and understanding of the benefits of minimally invasive surgery and possibly assist physicians to better manage future patients.

NCT ID: NCT00532870 Completed - Hernia, Ventral Clinical Trials

Laparoscopic Intraperitoneal Mesh Repair of Ventral Hernia: Comparison to Conventional Mesh Repair

Start date: March 2003
Phase: N/A
Study type: Interventional

The laparoscopic repair of ventral hernias is still a controversial therapeutic option. To evaluate the efficacy and safety of laparoscopic repair we compare the results of the open and laparoscopic repair of ventral hernia,. 53 patients were undergo laparoscopic or open repair of ventral hernia . All defects were estimated to be larger than 5 cm in diameter. Twenty six patients underwent attempted laparoscopic ventral hernia repair (LVHR) with mesh and twenty seven patients underwent open ventral hernia repair (OVHR) with mesh

NCT ID: NCT00528970 Completed - Ileus Clinical Trials

A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair

Start date: October 17, 2007
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of two different dose regimens (12 milligrams [mg] and 24 mg) of IV MOA-728 versus placebo in shortening the time to return of bowel function in participants receiving opioid analgesia administered via patient-controlled anesthesia (PCA), and who had undergone repair of large (greater than or equal to [≥]10 centimeters) ventral hernias with or without a mesh prosthesis via laparotomy or laparoscopy.

NCT ID: NCT00509054 Completed - Parastomal Hernia Clinical Trials

Prevention of Parastomal Hernia With a Mesh

Start date: January 2001
Phase: Phase 4
Study type: Interventional

Parastomal hernias are randomised to either a conventional stoma formed through the rectus anterior muscle or to the same procedure with the addition of a prophylactic mesh in a sublay position.

NCT ID: NCT00508053 Completed - Wound Infection Clinical Trials

When Closing Midline Incisions, do Small Stitches Reduce the Risk for Incisional Hernia, Wound Infection or Dehiscence?

Start date: January 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a technique using very small stitches when closing a midline incision can reduce the risk for wound complications such as incisional hernia, infection or dehiscence.

NCT ID: NCT00507377 Completed - Clinical trials for Gastroesophageal Reflux Disease

Foreshortened Esophagus and Its Surgical Therapy

GERDSurgery
Start date: September 2005
Phase:
Study type: Observational

Background The existence, diagnosis and treatment of short esophagus is one of the controversies of the past which has recently re-emerged The missed diagnosis of short esophagus and the consequent inadequacy of treatment is one of the major causes of failure of antireflux surgery. The daily clinical practice of surgeons dedicated to therapy of esophageal diseases could take advantage of the definition of frequency, preoperative predictors, intraoperative management and post operative outcomes of cases of foreshortened esophagus, in order to offer the patient affected by GERD the elements necessary for a conscious choice of therapy and to plan the best performance of the surgical procedure. Aims of the Study To define the percentage of cases among the total of antireflux procedures performed, in which, after standard isolation of the ge junction and eventual dissection of the mediastinal esophagus at least two centimetres of esophagus can not be replaced without any applied tension below the apex of the diaphragmatic hiatus. To define the percentage of surgical procedures aimed to treat electively a condition of non reducible G-E junction and foreshortened esophagus, among a multicentric formed case series of patients submitted to antireflux surgery. To define the preoperative clinical and instrumental predictors for a surgical procedure aimed to treat foreshortened esophagus. To record the intra-operative, postoperative, 6 month and 12 month outcome of procedures adopted for the surgical treatment of GERD. Materials and Methods The study will comprise patients in which surgical therapy for GERD is indicated according to the international guidelines and the Centres policy . Patients will be submitted to the antireflux procedure chosen by the surgeon according to the internationally recognized scientific surgical principles and the personal judgement. The preoperative study and the postoperative follow up adopted in the present study are accepted by the Centres as they correspond to the international guidelines and the Centres' current practice criteria for the surgical treatment of GERD.

NCT ID: NCT00496418 Completed - Hernia Clinical Trials

Peristomal Mesh for Prophylaxis of Parastomal Hernia

Start date: July 2007
Phase: Phase 3
Study type: Interventional

The study aims to prove differences or equalities in outcome for patients operated with or without a peristomal mesh in the sublay position when establishing a permanent colostomy.

NCT ID: NCT00492804 Completed - Inguinal Hernia Clinical Trials

Elective Neurectomy During Inguinal Hernia Repair

Start date: July 2005
Phase: Phase 2
Study type: Interventional

Chronic inguinal neuralgia is one of the most important complications following inguinal hernia repair. It may even outweigh the benefit of the operation. Intraoperative neurectomy has been investigated to reduce the incidence of chronic pain. This study evaluates the effects of elective division of the ilioinguinal, iliohypogastric and genital branch of the genitofemoral nerves on pain and postoperative sensory symptoms after Lichtenstein hernia repair.

NCT ID: NCT00485433 Completed - Postoperative Pain Clinical Trials

Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repair

Start date: June 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate three dose levels of SKY0402 compared with 105 mg of bupivacaine HCl.

NCT ID: NCT00478348 Completed - Clinical trials for Postoperative Complications

Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?

Start date: May 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether drainage after prosthetic repair of incisional abdominal hernias increases or decreases complications such as infection, seromas and hematomas.