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Hernia clinical trials

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NCT ID: NCT05953428 Recruiting - Hiatal Hernia Clinical Trials

Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia

Start date: November 14, 2023
Phase: N/A
Study type: Interventional

This is a prospective randomized, double-blinded, controlled trial that will enroll 75 subjects undergoing laparoscopic hiatal hernia repair surgery. Participants who meet eligibility criteria will be randomized in a 1:1 ratio to receive either the opioid sparring anesthesia protocol (OSA) or the opioid based anesthesia protocol (OBA). The purpose of this study is to investigate if an opioid sparring protocol for laparoscopic hiatal hernia repair will reduce opioid consumption during discharge. Other outcomes include: postoperative VAS scores (PACU arrival, PACU discharge, hospital discharge), total in hospital opioid consumption, PACU length of stay, incidence of postoperative nausea and vomiting (PONV in PACU, postoperative day 1, during hospital stay), rehospitalization rate, rate of reoperation, rate of emergency room visit, surgeon satisfaction, and hospital cost differential.

NCT ID: NCT05939687 Recruiting - Surgery Clinical Trials

Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection

ProMeLAR
Start date: June 5, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the efficacy of using polypropylene mesh for hernia prevention after stoma closure in patients with colorectal cancer and non-mesh repair. The main question it aims to answer is: can mesh help prevent hernia? Participants will be divided into 2 groups: with and without mesh using. They must be followed up for 2 years after enrollment in the study. Researchers will compare mesh and non-mesh groups to evaluate the benefits and harms of mesh using in hernia prevention.

NCT ID: NCT05934266 Recruiting - Postoperative Pain Clinical Trials

Impact of Mesh Fixation With Tissue Adhesive

Start date: March 29, 2023
Phase: Phase 4
Study type: Interventional

Randomized controlled trial on mesh fixation using cyanoacrylate glue compared to standard suture in open inguinal hernia repair.

NCT ID: NCT05929937 Recruiting - Postoperative Pain Clinical Trials

No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

Start date: July 10, 2023
Phase: Phase 3
Study type: Interventional

The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality of life at 30 days in either group.

NCT ID: NCT05929378 Recruiting - Chronic Pain Clinical Trials

A Comparative Study of 3-point With 1-point Mesh Fixation in TAPP for Gilbert Type III Inguinal Hernia

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This study was designed to compare the outcome of 3 point with 1 point lightweight mesh fixation in TAPP surgery for patients with type Ⅲ gilbert inguinal hernia. The main outcome include seroma, chronic pain, recurrence, et al.

NCT ID: NCT05927051 Recruiting - Clinical trials for Lumbar Disc Herniation

Effects of Exercise in Lumbal Disc Herniation

Start date: July 20, 2023
Phase: N/A
Study type: Interventional

Lumbar disc herniation, which causes 5% of all low back pain, is the rupture of the annulus fibrosis in the intervertebral disc in the lumbar region and the protrusion of the nucleus pulposus at various degrees, and as a result, the spinal cord or the nerves arising from it are compressed.Aerobic exercise is one of the most important elements in low back pain rehabilitation.Many studies have shown that individuals with low back pain have low muscle strength of the back extensors and flexors when compared to individuals who do not show symptoms, and that these muscles are strong and their aerobic fitness is high, minimizing trauma-related musculoskeletal damage.The aim of this study is to examine the effect of core stabilization exercises on functionality and core muscles in patients with LDH.

NCT ID: NCT05920200 Recruiting - Chronic Pain Clinical Trials

Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations

Start date: January 9, 2020
Phase:
Study type: Observational

The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia depending on surgical technique, mesh type and fixation suture material. For this purpose the investigators will analyze data from the Kalinigrad Hernia Registry (KHR).

NCT ID: NCT05918367 Recruiting - Surgery Clinical Trials

Multicenter Ventral Mesh Rectopexy Registry Collaborative

M2R2
Start date: September 25, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal prolapse or combined) by laparoscopy or robotic surgery and to evaluate the longterm functional outcomes. Secondly complications (mesh erosions, recurrence, reoperations) are evaluated. Following main questions will be analysed - other can follow in consultation with the collaborative 1. Is VMR the technique of choice for treatment of rectoceles? Functional results - recurrence - mesh related complications 2. Has a perineal descent an impact on the functional outcome of ventral mesh rectopexy perfored for external rectal prolaps, internal rectal prolaps, rectocele, enterocele, sigmoidcele or combined pelvic organ prolapse?

NCT ID: NCT05906017 Recruiting - Abdominal Hernia Clinical Trials

Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

In this randomized clinical trial, the investigators will compare the conventional open repair for hernia in the anterior abdominal wall with the robotic-assisted approach. 110 patients with midline abdominal wall defects will be randomized to either open or robotic-assisted surgery. The investigators will examine short and long-term complications through follow-up with clinical assessment as well as patient-reported outcome measures including pain, cosmetic appearance, and overall patient satisfaction. Furthermore, the investigators will study the difference in surgical stress response between the two methods measured from a variety of different biomarkers before and after the operation. A cost-effective analysis will be conducted for the robotic and open procedure.

NCT ID: NCT05896072 Recruiting - Post Operative Pain Clinical Trials

Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair

Start date: May 8, 2023
Phase: N/A
Study type: Interventional

Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used methods in postoperative pain control. Main purpose of this study is to compare the analgesic effect of ultrasound-guided erector spinae plane block and caudal block in pediatric unilateral inguinal hernia operations