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Hemorrhoids clinical trials

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NCT ID: NCT02061176 Active, not recruiting - Hemorrhoids Clinical Trials

THD Versus Open Haemorrhoidectomy

Start date: October 2013
Phase: N/A
Study type: Interventional

A randomised study comparing Transanal Haemorrhoidal Dearterialization (THD) and Open Haemorrhoidectomy (OH) for the treatment of prolapsing haemorrhoids. The primary aim of the study is to evaluate the long-term effect on haemorrhoidal symptoms one year postoperatively. Secondary endpoints are postoperative pain, complications, effect on anal continence, recovery and return to normal activity, quality of life and health cost analysis.

NCT ID: NCT02046772 Completed - Clinical trials for Surgical Remove of Hemorrhoids

Safety and Efficacy of the Addition of Morphine Chloride to a Low Dose of Bupivacaine as Intradural Anaesthetic for the Removal Surgery of the Hemorrhoids

Start date: March 2012
Phase: Phase 4
Study type: Interventional

A single blind, randomized, with blinded evaluation by third parties clinical trial is carried out to assess the analgesic efficay of the addition of morphine chloride to a low dose solution of spinal local anaesthetic compared to a standard dose spinal anaesthetic in the haemorrhoid surgery. The objective of this clinical trial is to assess if the experimental treatment is as efficacy as the standard treatment in the anesthetic and analgesic effects with less side effects, greater and earlier mobility after surgery and shortened the hospitalization.

NCT ID: NCT02039570 Not yet recruiting - Haemorrhoids Clinical Trials

The Relationship Between Haemorrhoids and Pelvic Vein Reflux

Start date: March 2014
Phase: N/A
Study type: Observational

This case series aims to find out in a group of female patients suffering from haemorrhoids, how many of them have pelvic vein reflux that feeds into their haemorrhoids. This will be done by examining their ovarian and internal iliac veins for reflux, using a transvaginal scan.

NCT ID: NCT02010099 Completed - Clinical trials for Bleeding Hemorrhoids

A Prospective, Randomized, Three Arms, Open Label Study Comparing the Safety and Efficacy of Two Formulations of PP110 to the Active Comparator Preparation-H® Cream in the Treatment of Bleeding Hemorrhoids Grades 2-3

Start date: November 2013
Phase: Phase 2/Phase 3
Study type: Interventional

Eligible patients with bleeding hemorrhoids of grade 2-3 are randomized to test-1 product (PP110 Gel), test-2 product (PP-110 medicated wipes) or control (Preparation-H cream). Test product usage: once daily, about 1-5 minutes prior to first bowel movement. Control product usage: according to label, 3-4 times daily application to rectal region. At the end of each day, subject fills a questionnaire regarding bleeding, pain, discharge, swelling, itching, discomfort and painkiller usage. Treatment is for two weeks, after which subjects fill a feedback questionnaire addressing treatment efficacy and subject satisfaction. Also, at the end of two weeks, subjects are examined by study physician who assesses hemorrhoid severity.

NCT ID: NCT01961739 Recruiting - Hemorrhoids Clinical Trials

Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids

H1-5
Start date: October 2013
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of topical 2% lidocaine in the therapy of symptomatic hemorrhoids. Efficacy will be determined by: 1. the change from baseline in pain, itching, bleeding, swelling, discomfort, general well-being and improvement since the beginning of treatment as separate components of CORRECTS scale 2. the change in overall CORRECTS values from baseline 3. the change in degree of hemorrhoids from baseline

NCT ID: NCT01927874 Completed - Hemorrhoid Clinical Trials

Subarachnoid or Infiltration for Hemorrhoidectomy

Start date: January 2013
Phase: N/A
Study type: Interventional

There will be compared the postoperative analgesic effect of infiltration or spinal block for hemorrhoidectomy

NCT ID: NCT01913158 Completed - Clinical trials for Internal Hemorrhoids

Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids

Start date: October 2013
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to determine the safety and efficacy of G&W Laboratories' Anucort HC TM (Hydrocortisone Acetate) 25mg Rectal Suppositories in subjects with internal hemorrhoidal symptoms.

NCT ID: NCT01881282 Completed - Hemorrhoids Clinical Trials

A Comparative Efficacy and Safety Study of Compound Carraghenates Cream With Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids

Start date: December 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the therapeutic effect and safety of compound carraghenates cream with Mayinglong musk hemorrhoid (swollen veins in the lower part of the rectum or anus) ointment in the treatment of hemorrhoids, especially regarding the relief of pain.

NCT ID: NCT01880775 Completed - Hemorrhoid Clinical Trials

Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl

Start date: April 2012
Phase: Phase 4
Study type: Interventional

In this prospective randomized study the investigators aimed to investigate difference of the duration of spinal anesthesia, discharge times and efficacy between low dose heavy Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl in outpatient minor anal surgery.

NCT ID: NCT01867944 Completed - Constipation Clinical Trials

Perineal Self-Acupressure

Start date: June 2013
Phase: N/A
Study type: Interventional

The primary aim of this study is to test a non-medicinal technique for chronic constipation. The core of the technique is to have subjects repeatedly press on and massage their perineum before defecation to fragment and soften the stool before it passes the lower rectum and anus. The technique will be evaluated as a complementary treatment to standard treatment of constipation (patient educational materials about treatments such as stool softeners, laxatives fiber supplements, and increased exercise). Although this technique has been studied for other conditions (for example in pregnant women to prevent birthing-related injuries), and it is recommended anecdotally by some physicians, this would be the first time it will be studied for chronic constipation in a randomized, controlled clinical trial. $50 dollars in compensation is provided for about an hour of participant's time.