Clinical Trials Logo

Hemorrhage clinical trials

View clinical trials related to Hemorrhage.

Filter by:

NCT ID: NCT03471702 Terminated - Clinical trials for Subarachnoid Hemorrhage

A Secondary Study Evaluating Aqueduct's Smart External Drain (SED)

Start date: February 28, 2018
Phase: N/A
Study type: Interventional

Aqueduct's Smart External Drain (SED) will be compared to the current gold standard for temporary CSF management in a hospital setting. - Evaluate the number of subjects requiring to be switched to a standard of care EVD - Evaluate subject transport while on the SED - Evaluate SED system control from initiation of SED through discharge of external drain system

NCT ID: NCT03413891 Terminated - Tooth Extraction Clinical Trials

Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extraction

EXTRACT-NOAC
Start date: February 7, 2018
Phase: Phase 4
Study type: Interventional

In patients treated with direct oral anticoagulants, bleeding events during or after tooth extraction can lead to unscheduled interruption of the antithrombotic treatment and a potential increased risk of thrombo-embolic events. Therefore, an optimal strategy to minimize bleeding events after tooth extractions is required. In this study, the investigators want to assess whether adding tranexamic acid mouthwash reduces the number of bleeding events in patients treated with direct oral anticoagulants and undergoing a tooth extraction.

NCT ID: NCT03305614 Terminated - Clinical trials for Aphasia Following Cerebral Infarction

tDCS and Aphasia Therapy in the Chronic Phase After Stroke

Start date: November 24, 2017
Phase: Phase 2
Study type: Interventional

This study evaluates the neuromodulatory effect of combined tDCS and aphasia therapy in patients in the chronic phase after stroke. Half of the participants will receive aphasia therapy and tDCS, the other half will receive aphasia therapy and sham-tDCS.

NCT ID: NCT03246919 Terminated - Pregnancy Related Clinical Trials

Ideal Time of Oxytocin Infusion During Cesarean Section

I-TOPICS
Start date: September 13, 2017
Phase: Phase 4
Study type: Interventional

This study will evaluate if the timing of oxytocin administration in cesarean deliveries will affect the amount of maternal blood loss. Half of participants will receive oxytocin after delivery of the fetal anterior shoulder and the other half will receive oxytocin after delivery of the placenta. We hypothesize that administering oxytocin after delivery of the shoulder, will result in less overall maternal blood loss.

NCT ID: NCT03194581 Terminated - Hemorrhage Clinical Trials

Normoxic Challenges Utility to Evaluate Blood Loss

Start date: October 1, 2017
Phase:
Study type: Observational

This study will evaluate the impact of repeated normoxic challenges on cerebral oxygenation as a measure of the effect of blood loss on DO2 during surgical procedures.

NCT ID: NCT03186157 Terminated - Stroke Clinical Trials

Prevalence of Trephined Syndrome After Decompressive Craniectomy

TS
Start date: January 16, 2012
Phase:
Study type: Observational

Decompressive craniectomy is frequently used to treat increased intracranial pressure or an intracranial mass effect. Trephined Syndrome describes a neurological deterioration, which is attributed to a large craniectomy. The symptomatology is varied but includes headache, aggravation of a hemisyndrome or cognitive disorders, often has an orthostatic component and improves or disappears with cranioplasty. The incidence of Trephined Syndrome has been reported between 7% and 26%. However, it might be underestimated if the course of cognitive functions before and after cranioplasty were insufficiently documented.

NCT ID: NCT03085394 Terminated - Tranexamic Acid Clinical Trials

Preoperative Hexakapron Reduces Bleeding in Bariatric Surgery

PHORBBS
Start date: September 1, 2017
Phase: Phase 3
Study type: Interventional

Prophylactic use of tranexamic acid to reduce intra and postoperative bleeding in primary sleeve gastrectomy procedures will be studied.

NCT ID: NCT03064152 Terminated - Clinical trials for Postpartum Hemorrhage

Rotational Thromboelastometry for the Transfusion Management of Postpartum Hemorrhage After Vaginal or Cesarean Delivery

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the impact of a rotational thromboelastometry (ROTEM®)-based transfusion protocol during postpartum hemorrhage (PPH) after vaginal or cesarean delivery. Maternal transfusion requirement, quantitative blood loss (QBL), need for intensive care unit (ICU) admission, and length of hospital stay will be evaluated. The utilization of ROTEM® for transfusion management will identify patients who develop early coagulation changes such as hypofibrinogenemia or disseminated intravascular coagulation. Our hypothesis is that earlier identification and directed therapy of such coagulation changes will lower overall transfusion requirement (packed red blood cells, fresh frozen plasma, fibrinogen concentrate, cryoprecipitate, or other product), reduce the need for ICU admission, and shorten length of hospital stay. A cost analysis will be performed.

NCT ID: NCT03032471 Terminated - Stroke Clinical Trials

Swiss SOS MoCA - DCI Study

Start date: July 20, 2017
Phase:
Study type: Observational

The primary objective of this multicenter observational study is to determine the effect size of the relationship between DCI and neuropsychological impairment 14-28 days and 3 months after aSAH. Secondary objectives are the feasibility to administer and the validity of the MoCA in an intensive care unit setting, as well as the test/retest reliability of the MoCA in patients with acute brain damage in absence of aSAH.

NCT ID: NCT02999100 Terminated - Clinical trials for Postpartum Hemorrhage

Comparison of Inhaled Oxytocin (IH) With Intramuscular (IM) Oxytocin in Pregnant Women and With Intravenous (IV) Oxytocin in Healthy Non-pregnant Women

Start date: November 23, 2016
Phase: Phase 1
Study type: Interventional

The study will evaluate a stable, dry-powder formulation of oxytocin, with the goal of reducing post-partum hemorrhage morbidity and mortality in resource poor settings. This study is being conducted to further assess safety and tolerability of inhaled oxytocin, and to characterize the drug levels of inhaled (IH) oxytocin when compared to oxytocin administered as standard of care. Two groups of subjects will be enrolled. Group 1 will enroll pregnant women, who will be randomized to receive either IH or intramuscular (IM) oxytocin as active management of the third stage of labour (after the baby is born). Group 2 will enroll non-pregnant women of childbearing potential, who will receive IH oxytocin and intravenous (IV) oxytocin in a cross over design over two dosing sessions This group will evaluate the safety and tolerability of IH and IV oxytocin.