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Hemiplegia clinical trials

View clinical trials related to Hemiplegia.

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NCT ID: NCT05138185 Completed - Clinical trials for Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)

Proof-of-concept of a Robotic Knee Exoskeleton in Healthy Subjects and Hemiparetic Patients During Gait.

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Hemiparetic gait is characterized by strong asymmetries that could severely affect the quality of life of stroke survivors. This asymmetry is due to motor deficits in the paretic leg and the resulting compensations in the non-paretic limb. In this study, the investigators aim to evaluate the effect of actively promoting gait symmetry in hemiparetic patients by assessing the behavior of both paretic and non-paretic lower limbs. To this end, the investigators use a unilateral active Knee-Ankle-Foot Orthosis able to assist the paretic limb of hemiparetic patients during gait. The system is able to synchronize its action with the movement of the unassisted joints, promoting a natural and intuitive interaction. The device generate the assistance according to two differents strategies: (1) Replicating the movement of the helathy leg or (2) Inducing a healthy gait pattern on the paretic leg. The hypothesis is that a proper and natural interaction between the user and the exoskeleton would enable the patients to consider the robot action as a part of their own gait capability, improving their gait quality as consequence. Hemiparetic asymmetry is not only due to impairments in the affected limb, but also it is the consequence of biomechanical compensatory mechanisms that might arose in the non-paretic leg. We aim to assess the adaptation process of the subject to the exoskeleton assistance, and to evaluate the effects of such human-robot interaction in both paretic and non-paretic legs.

NCT ID: NCT05134272 Completed - Cerebral Palsy Clinical Trials

Infant Modified Constraint Induced Movement Therapy Paired With Neuromuscular Electrical Stimulation: a Case Series

Start date: November 17, 2021
Phase:
Study type: Observational

This study will compare the motor outcomes for five infants with asymmetrical hand function (AHF) who will receive two, three week episodes of standard care separated by a three week episode of mCIMT paired with Neuromuscular Electrical Stimulation. The results of this study will inform decisions on the feasibility and efficacy of the treatment for use in a larger study for infants with AHF at risk for unilateral cerebral palsy.

NCT ID: NCT05106543 Completed - Hemiplegia Clinical Trials

Immediate Effect Of Kinesiological Taping

Start date: January 5, 2020
Phase: N/A
Study type: Interventional

In this study, it is aimed to examine the immediate effect of kinesiological taping on functionality in hemiplegic patients. 40 hemiplegic patients with a mean age of 63±15 years were included to the study. The patients were divided into two groups using the computerized randomization method. Kinesiology tape was applied to the 1st group (study group), and a patch tape was applied to the 2nd group (control group). The demographic and physical characteristics of the people who agreed to participate in the study were recorded. In both groups; before taping, right after taping, 45 min. after and 4 days after taping Timed Get Up and Go Test (TUG) were administered. Both groups were asked not to remove the tapes at the end of the 4th day.

NCT ID: NCT05101707 Completed - Hemiplegia Clinical Trials

CIMT and taVNS for Hemiplegia in Infants

Start date: April 1, 2022
Phase: Early Phase 1
Study type: Interventional

Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body. In older children, therapists may use a hand mitt and restraint for the stronger arm, to encourage use of the weaker side, called constraint-induced movement therapy (CIMT). Even with the high intensity therapy of CIMT, it typically takes between 40-120 hours total treatment time for most children to improve their motor skills. A non-invasive form of nerve stimulation, transcutaneous auricular vagus nerve stimulation (taVNS), stimulates a nerve by the ear that enhances learning motor skills. The purpose of this study is to evaluate the safety and effectiveness of taVNS to improve motor skills when paired with CIMT in infants with one-sided weakness at 6-18months of age.

NCT ID: NCT05069480 Completed - Clinical trials for Upper Extremity Dysfunction

Modulation of Upper Limb Spasticity Post-Stroke

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Stroke is one of the commonest causes of severe disability in adults. Stroke often results in spasticity and motor impairments in the upper limb. Permanent upper extremity impairments can lead to limitations in activities of daily living, social participation, and quality of life. Spasticity may obscure motor learning ability after stroke. Spasticity control is one of the main aims of most therapists in the rehabilitation process for patients with chronic stroke. Traditional approaches for managing spasticity may not be enough for gaining satisfactory results. Virtual reality-based therapy is one of the most innovative and developments in rehabilitation technology. It could be effective in accelerating motor recovery and modulating spasticity for the involved upper limbs. The purpose of this study was to examine the impact of virtual reality-based therapy on upper limb spasticity and motor functions in patients post-stroke.

NCT ID: NCT04944927 Completed - Clinical trials for Alternating Hemiplegia of Childhood

HEmiplegia Arrhythmia Retrospective Trial

HEART
Start date: April 29, 2021
Phase:
Study type: Observational

Alternating Hemiplegia of Childhood (AHC) is a rare and severe disease that is in need of effective, and hopefully even curative, therapies. Afflicted patients suffer from severe paralyzing crises, often excruciatingly painful muscle spasms, severe often life threatening epileptic seizures, frequently severe developmental and psychiatric/psychological disabilities and other comorbidities, such as cardiac disturbances. Recent data indicate that AHC genotype is in relation to cardiac repolarization troubles and to cardiac arrhythmias. The primary hypothesis to explore is that there is an association between genotype and cardiac phenotype in AHC.

NCT ID: NCT04939493 Completed - Hemiplegia, Spastic Clinical Trials

Use of Rhythmic Auditory Cueing During Bilateral Training of the Upper Extremities in Stroke Patients

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effect of rhythmic auditory cueing with bilateral arm training on upper limb functions in stroke patients.

NCT ID: NCT04894097 Completed - Hemiplegia Clinical Trials

Effect of Radial Extracorpeal Shock Wave on Pain and Function

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

The purpose of the current study will be focused on the following issues. Evaluation of the effect of radial extracorporeal shock wave on the pressure pain threshold and disability in stroke hemiplegic shoulder.

NCT ID: NCT04889586 Completed - Stroke Clinical Trials

Hand MOtor Rehabilitation Using a EMG-biofeedback: a Cross-sectional Study

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Start date: July 25, 2017
Phase: N/A
Study type: Interventional

Recovery of upper limb and hand gestures is fundamental for autonomy restoration after stroke. Innovative technologies are a valid support for the delivery of rehabilitation treatments. Embedding surface electromyographic (sEMG) into wearable devices, allows the customisation of rehabilitation exercises, based on the clinical profile of each patient.

NCT ID: NCT04859673 Completed - Hemiplegia Clinical Trials

Influence of Radial Extracorpeal Shock Wave in Hemiplegic Shoulder Patients

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The purposes of this study are to examine sonographic structural changes pre and post the radial extracorporeal shock wave intervention in hemiplegic shoulder pain, and to assess the relationships between sonographic structural changes and hemiplegic shoulder pain.