Aldana SG Financial impact of health promotion programs: a comprehensive review of the literature. Am J Health Promot. 2001 May-Jun;15(5):296-320. doi: 10.4278/0890-1171-15.5.296.
Bhammar DM, Sawyer BJ, Tucker WJ, Gaesser GA Breaks in Sitting Time: Effects on Continuously Monitored Glucose and Blood Pressure. Med Sci Sports Exerc. 2017 Oct;49(10):2119-2130. doi: 10.1249/MSS.0000000000001315.
Biswas A, Oh PI, Faulkner GE, Bajaj RR, Silver MA, Mitchell MS, Alter DA Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis. Ann Intern Med. 2015 Jan 20;162(2):123-32. doi: 10.7326/M14-1651. Erratum In: Ann Intern Med. 2015 Sep 1;163(5):400.
Borsci S, Federici S, Lauriola M On the dimensionality of the System Usability Scale: a test of alternative measurement models. Cogn Process. 2009 Aug;10(3):193-7. doi: 10.1007/s10339-009-0268-9. Epub 2009 Jun 30.
Davis KG, Kotowski SE Postural variability: an effective way to reduce musculoskeletal discomfort in office work. Hum Factors. 2014 Nov;56(7):1249-61. doi: 10.1177/0018720814528003.
Elo AL, Leppanen A, Jahkola A Validity of a single-item measure of stress symptoms. Scand J Work Environ Health. 2003 Dec;29(6):444-51. doi: 10.5271/sjweh.752.
Falck RS, Davis JC, Liu-Ambrose T What is the association between sedentary behaviour and cognitive function? A systematic review. Br J Sports Med. 2017 May;51(10):800-811. doi: 10.1136/bjsports-2015-095551. Epub 2016 May 6.
Fang Q, Ghanouni P, Anderson SE, Touchett H, Shirley R, Fang F, Fang C Effects of Exergaming on Balance of Healthy Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Games Health J. 2020 Feb;9(1):11-23. doi: 10.1089/g4h.2019.0016. Epub 2019 Dec 3.
Gao Y, Nevala N, Cronin NJ, Finni T Effects of environmental intervention on sedentary time, musculoskeletal comfort and work ability in office workers. Eur J Sport Sci. 2016 Sep;16(6):747-54. doi: 10.1080/17461391.2015.1106590. Epub 2015 Nov 3.
Klompstra L, Jaarsma T, Stromberg A Exergaming to increase the exercise capacity and daily physical activity in heart failure patients: a pilot study. BMC Geriatr. 2014 Nov 18;14:119. doi: 10.1186/1471-2318-14-119.
Knols RH, Fischer N, Kohlbrenner D, Manettas A, de Bruin ED Replicability of Physical Exercise Interventions in Lung Transplant Recipients; A Systematic Review. Front Physiol. 2018 Jul 20;9:946. doi: 10.3389/fphys.2018.00946. eCollection 2018.
Konstantinidis EI, Billis AS, Mouzakidis CA, Zilidou VI, Antoniou PE, Bamidis PD Design, Implementation, and Wide Pilot Deployment of FitForAll: An Easy to use Exergaming Platform Improving Physical Fitness and Life Quality of Senior Citizens. IEEE J Biomed Health Inform. 2016 Jan;20(1):189-200. doi: 10.1109/JBHI.2014.2378814.
Li J, Theng YL, Cheong WL, Hoo YF, Ngo MD Exergames for the corporate wellness program in Singapore: An investigation of employees' acceptance via watching Kinect video. Digit Health. 2016 Jun 17;2:2055207616654578. doi: 10.1177/2055207616654578. eCollection 2016 Jan-Dec.
Meekes W, Stanmore EK Motivational Determinants of Exergame Participation for Older People in Assisted Living Facilities: Mixed-Methods Study. J Med Internet Res. 2017 Jul 6;19(7):e238. doi: 10.2196/jmir.6841.
Moore CG, Carter RE, Nietert PJ, Stewart PW Recommendations for planning pilot studies in clinical and translational research. Clin Transl Sci. 2011 Oct;4(5):332-7. doi: 10.1111/j.1752-8062.2011.00347.x.
Rebsamen S, Knols RH, Pfister PB, de Bruin ED Exergame-Driven High-Intensity Interval Training in Untrained Community Dwelling Older Adults: A Formative One Group Quasi- Experimental Feasibility Trial. Front Physiol. 2019 Aug 7;10:1019. doi: 10.3389/fphys.2019.01019. eCollection 2019.
Schellewald V, Kleinert J, Ellegast R Effects of two types of dynamic office workstations (DOWs) used at two intensities on cognitive performance and office work in tasks with various complexity. Ergonomics. 2021 Jun;64(6):806-818. doi: 10.1080/00140139.2020.1862308. Epub 2020 Dec 23.
Shikiar R, Halpern MT, Rentz AM, Khan ZM Development of the Health and Work Questionnaire (HWQ): an instrument for assessing workplace productivity in relation to worker health. Work. 2004;22(3):219-29.
Teychenne M, Ball K, Salmon J Sedentary behavior and depression among adults: a review. Int J Behav Med. 2010 Dec;17(4):246-54. doi: 10.1007/s12529-010-9075-z.
van het Reve E, de Bruin ED Strength-balance supplemented with computerized cognitive training to improve dual task gait and divided attention in older adults: a multicenter randomized-controlled trial. BMC Geriatr. 2014 Dec 15;14:134. doi: 10.1186/1471-2318-14-134.
Zheng L, Li G, Wang X, Yin H, Jia Y, Leng M, Li H, Chen L Effect of exergames on physical outcomes in frail elderly: a systematic review. Aging Clin Exp Res. 2020 Nov;32(11):2187-2200. doi: 10.1007/s40520-019-01344-x. Epub 2019 Sep 13.
Usability and Feasibility Trial of an Exergame-based Occupational Health Intervention at Two Swiss Workforce Companies
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.