Efficacy of Movement Breaks in Real-World Settings

Healthy Clinical Trial

Official title:

Efficacy of Movement Breaks in Real-World Settings

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05574426
• Other study ID #: H21-03417
• Secondary ID: 707246POC-181042
• Status: Completed
• Phase: N/A
• Start date: October 1, 2022
• Est. completion date: December 5, 2023

Study information

• Verified date: December 2023
• Source: University of British Columbia
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine the efficacy of performing "exercise snacks" (short movement breaks throughout the day) on various measures of cardiometabolic health.

Description:

After being informed about the study and potential risks, all eligible participants who have provided consent will undergo a baseline visit to assess pre-intervention basic anthropometrics, cardiorespiratory fitness, and provide a blood sample. Participants will then be randomized in a 1:1 ratio to one of two groups: 1) Mobility movement breaks (stretching or range of motion exercises); or 2) Cardiovascular movement breaks (designed to raise heart rate). Both groups will be encouraged to perform 3-4 daily movement breaks on at least 3 days of the week with support from an online platform and app that provides video instructions and reminders to complete the movement breaks. After 12 weeks, participants will be asked to return to the lab for the same testing performed at baseline.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 77
• Est. completion date: December 5, 2023
• Est. primary completion date: December 5, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years to 64 Years

Eligibility

Inclusion Criteria:

1. Physically inactive (performing <150 minutes of moderate-to-vigorous intensity aerobic exercise per week, assessed by pre-screening Get Active Questionnaire);

2. Body Mass Index: 18.5-30.0 kg/m2;

3. Not currently diagnosed with or being treated for cardiometabolic disease (e.g., coronary artery disease, diabetes);

4. Not a current smoker;

5. Cleared to engage in physical activity using the Get Active Questionnaire and, if applicable, consultation with a Qualified Exercise Professional;

6. Access to a computer, tablet or smartphone for intervention delivery and tracking

Exclusion Criteria:

1. Chronic health condition preventing participation in exercise;

2. Lack of access to internet connection

Related Conditions & MeSH terms

• Healthy

Intervention

Behavioral:
• Movement Breaks
Participants will be asked to perform 30-60 second movement breaks 3-4 times per day on at least 3 days per week.

Locations

Country	Name	City	State
Canada	McMaster University	Hamilton	Ontario
Canada	University of British Columbia	Kelowna	British Columbia

Sponsors (4)

Lead Sponsor	Collaborator
University of British Columbia	Canadian Cancer Society (CCS), Canadian Institutes of Health Research (CIHR), McMaster University

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from Baseline in Cardiorespiratory Fitness at 12 Weeks	Cardiorespiratory fitness will be assessed as the highest 30-s average from a laboratory-based graded VO2peak test on a cycle ergometer.	Baseline and Week 12
Secondary	Change from Baseline in Plasma Insulin	A fasted venous blood sample will be obtained and insulin measured by commercial assay.	Baseline and 12 weeks
Secondary	Change from Baseline in Plasma Glucose	A fasted venous blood sample will be obtained and glucose measured by biochemical assay.	Baseline and 12 weeks
Secondary	Change from Baseline in Insulin Resistance	A fasted venous blood sample will be obtained and insulin resistance estimated by homeostasis model assessment (HOMA) score	Baseline and 12 weeks
Secondary	Change from Baseline in Inflammatory cytokines	A fasted venous blood sample will be obtained and inflammatory cytokines measured by multiplex assay	Baseline and 12 weeks
Secondary	Change from Baseline in Body Mass	Body mass will be measured by weigh scale	Baseline and 12 weeks
Secondary	Change from Baseline in Waist Circumference	Waist circumference (in centimetres) will be measured using a measurement tape.	Baseline and 12 weeks
Secondary	Device-Measured Adherence to Movement Breaks	Participants will wear accelerometers to assess adherence near the beginning and the end of the intervention.	Week 2 and week 11
Secondary	Self-Reported Adherence to Movement Breaks	Participants will be sent weekly surveys asking them to recall the total number of movement breaks performed that week.	Once per week for 12 weeks
Secondary	Movement Break Enjoyment assessed by the Exercise Enjoyment Scale (EES)	The EES is a validated, single-item 7-point scale to assess exercise enjoyment. Possible scores range from 1 (not at all) to 7 (extremely).	Immediately following each movement break for entire 12-week intervention
Secondary	Rating of Perceived Exertion (RPE) following Movement Breaks	A 10 point RPE scale will be used to assess perceived exertion ranging from 0 (rest) to 10 (maximal).	Immediately following each movement break for entire 12-week intervention