The Application of Neuromodulation in Sciatic Nerve

Healthy Clinical Trial

Official title:

The Fascicular Anatomy of Nerve May Influence the Muscular Activity of the Biceps Femoris After Applying Ultrasound-guided Percutaneous Neuromodulation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05549700
• Other study ID #: Sciatic nerve and NMP
• Status: Completed
• Phase: N/A
• Start date: December 1, 2022
• Est. completion date: December 30, 2022

Study information

• Verified date: December 2022
• Source: University of Seville
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The objective of this study will be to analyze the muscle activity of the short head (SHBF) and long head of the biceps femoris (LHBF) after the application of ultrasound-guided percutaneous neuromodulation (NMP) in the tibial or common fibular nerve compartment of the sciatic nerve.

Authors will recruit healthy subjects and they will receive asymmetric biphasic rectangular current through a needle into the sciatic nerve. The sample was divided into two groups: one to which the technique was applied in the lateral compartment and another group, in the medial compartment of the nerve. The protocol used was 5 seconds of stimulation, 55 seconds of rest for 5 minutes at a frequency of 100 Hz and a phase duration of 350 microseconds. The electrical activity (recruitment of muscle fibers and maximum contraction) of the SHBF and LHBF and the muscle strength of the knee flexors were recorded by requesting the participants isometric flexion of the knee in the prone position. The percentage of change of each variable was also analyzed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38
• Est. completion date: December 30, 2022
• Est. primary completion date: December 2, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Healthy volunteer

Exclusion Criteria:

• Subjects that have lumbar area of the back, scoliosis, lower limb dysmetria

• Subjects undergone any surgical intervention in the lumbar area or lower limbs

• Subjects that present acute or unresolved injury in the last 6 months in the lower limbs

• Subjects under treatment drug treatment

• Subjects that they are afraid of needles or electric current

• Subjects with epileptic

• Pregnant.

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• Neuromodulation
Ultrasound-guided percutaneous neuromodulation will be applied. The protocol used was 5 seconds of stimulation, 55 seconds of rest for 5 minutes at a frequency of 100 Hz and a phase duration of 350 microseconds

Locations

Country	Name	City	State
Spain	Blanca	Seville	Sevile

Sponsors (1)

Lead Sponsor	Collaborator
University of Seville

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Electrical muscular activity	recruitment of muscle fibers, measured by electromyography (microvolts)	3 months
Primary	muscle strength of the knee flexors	strength measured by dynamometer (Kg)	3 months