NCT04994379 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Vicario CM, Rafal RD, Borgomaneri S, Paracampo R, Kritikos A, Avenanti A
Pictures of disgusting foods and disgusted facial expressions suppress the tongue motor cortex. Soc Cogn Affect Neurosci. 2017 Feb 1;12(2):352-362. doi: 10.1093/scan/nsw129.
Vicario CM, Salehinejad MA, Mosayebi-Samani M, Maezawa H, Avenanti A, Nitsche MA
Transcranial direct current stimulation over the tongue motor cortex reduces appetite in healthy humans. Brain Stimul. 2020 Jul - Aug;13(4):1121-1123. doi: 10.1016/j.brs.2020.05.008. Epub 2020 May 12.

Investigating the Effect of the Intensity of Primary Motor Cortex Cathodal tDCS on Appetite; A Double-blind Sham-controlled Study

Clinical trial NCT04994379 - References