Can Mimic Emotional Expression Training Help Improve Emotion Processing

Healthy Clinical Trial

Official title:

Can Mimic Emotional Expression Training Help Improve Emotion Processing

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04922684
• Other study ID #: UESTC-neuSCAN-66
• Status: Recruiting
• Phase: N/A
• Start date: March 30, 2020
• Est. completion date: March 30, 2022

Study information

• Verified date: June 2021
• Source: University of Electronic Science and Technology of China
• Contact: Keith Kendrick, Dr.
• Phone: 86-28-61830811
• Email: k.kendrick.uestc[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The main aim of the present study is to investigate whether mimicking emotional expressions training via FaceReader software can improve emotional processing and recognition in healthy subjects, especially individuals with hityer autistic traits.

Description:

Some mood and trait questionnaires such as Autism Spectrum Quotient, Social Responsiveness Scale,State-Trait Anxiety Inventory,Beck's Depression Inventory etc are asked to complete. 90 healthy male subjects will receive 16 times (4 times a week , 4 weeks) of mimicking emotional expressions training via Facereader. During training, 3 times of fNIRS (t2,t9 and t16) were recorded simultaneously. fMRI scanning, including emotion processing and emotion recognition tasks, 7 minutes resting data, ans DTI data will be collected before and after the training. After fMRI scaning, behavioral ratings (i.e. intensity and valence) and eye-tracking data will be collected.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: March 30, 2022
• Est. primary completion date: December 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 17 Years to 30 Years

Eligibility

Inclusion Criteria:

• Healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria:

• history of head injury;

• pregnant, menstruating, taking oral contraceptives;

• medical or psychiatric illness.

Related Conditions & MeSH terms

• Healthy

Intervention

Behavioral:
• Mimic facial expressions
16 times (4 times a week, last 4 weeks) of mimicking facial expressions.

Locations

Country	Name	City	State
China	University of Electronic Science and Technology of China	Chengdu	Sichuan

Sponsors (1)

Lead Sponsor	Collaborator
University of Electronic Science and Technology of China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intensity score of subjects' mimic facial emotions	The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into intensity, ranging from 0 to 1.	an average of 4 weeks
Primary	Valence score of subjects' mimic facial emotions	The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into valence, ranging from -1 to 1.	an average of 4 weeks
Primary	Arousal score of subjects' mimic facial emotions	The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into arousal, ranging from 0 to 1.	an average of 4 weeks
Primary	Task-dependent functional MRI data	Neural activities of brain regions, notably mirror neuron system will be collected for analysis when the subjects participate in a face processing and emotion recognition task in a MRI scanner before and after the 4-week training session.	an average of 4 weeks