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Brain, Behavior and Endocrine Effects of Transcutaneous Vagus Nerve Stimulation

Healthy Clinical Trial

Official title:
Transcutaneous Vagus Nerve Stimulation Promotes Oxytocin Release and Increases Fixations on Nose

Clinical Trial Summary

The main aim of the study is to investigate whether the transcutaneous vagus nerve stimulation(tVNS) promotes oxytocin release and the potential biomarkers of tVNS based on eye-tracking data

Clinical Trial Description

A randomized, single-blinded, sham-controlled, within-subject, crossover design will be employed in this study. In a randomized order, a total of 54 healthy subjects will receive transcutaneous vagus nerve stimulation via tragus and sham stimulation vis earlobe in the left ear (interval between these two stimulations will be 1 week). Eye-tracking and behavioral data will be collected before and after 30 minutes of stimulation, saliva samples will be collected before and after 30 minutes of stimulation, and the end of the experiment. Some personal traits will be assessed using different kinds of questionnaires, such as the Autism Spectrum Quotient(ASQ), Social Responsiveness Scale(SRS), State-Trait Anxiety Inventory (STAI), Beck's Depression Inventory(BDI), and Toronto Alexithymia Scale (TAS-20). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04890457
Study type Interventional
Source University of Electronic Science and Technology of China
Contact Keith Kendrick, Dr.
Phone 86-28-61830811
Email k.kendrick.uestc@gmail.com
Status Recruiting
Phase N/A
Start date March 5, 2021
Completion date December 30, 2021
View Details
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