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NCT ID: NCT04931524 Recruiting - Healthy Clinical Trials

A Study to Assess the Absorption, Metabolism and Excretion of [14C]-ANG-3777

Start date: May 21, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the mass balance recovery and metabolic profiling and identification of 14C-ANG-3777 administered as a single IV dose.

NCT ID: NCT04922684 Recruiting - Healthy Clinical Trials

Can Mimic Emotional Expression Training Help Improve Emotion Processing

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

The main aim of the present study is to investigate whether mimicking emotional expressions training via FaceReader software can improve emotional processing and recognition in healthy subjects, especially individuals with hityer autistic traits.

NCT ID: NCT04920539 Recruiting - Healthy Clinical Trials

In Vivo Study of THC-induced Immune-genome Changes at Single Cell Solution in HIV-infected Humans

Start date: February 8, 2022
Phase: Phase 1
Study type: Interventional

In this study, the investigators hypothesize that THC alters the immunogenome in a cell type-specific fashion and alters cytokine production via epigenetic regulatory mechanisms and that these alterations differ between HIV-infected and HIV-uninfected host genomes.

NCT ID: NCT04903600 Recruiting - Healthy Clinical Trials

Efficacy Assessment of Probiotics Product on Intestinal Health and Immune System Improvement

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of probiotics product (probiotics fruit vegetable fiber powder) on intestinal health and immune system improvement in adults

NCT ID: NCT04894422 Recruiting - Healthy Clinical Trials

Microbiome Analysis of Skin and Airway Samples and Effect of Face Masks

Start date: March 15, 2021
Phase:
Study type: Observational

The goal of this study is to optimize two methods for microbiome analysis of skin and upper airway samples (16S amplicon sequencing and Shotgun sequencing). In addition, the researchers will investigate whether there is an effect of wearing a face mask on the microbial communities of the skin and upper airways. The volunteers will self-collect swabs of the skin and upper airways (nose and/or throat). Bacterial DNA and/or total RNA will be isolated and the microbial communities will be investigated with 16S amplicon sequencing and shotgun metagenomic sequencing.

NCT ID: NCT04893798 Recruiting - Healthy Clinical Trials

A Study Comparing Subcutaneous Injection of Sayana Press In the Upper Arm Versus Anterior Thigh and Abdomen

Start date: September 16, 2021
Phase: Phase 1
Study type: Interventional

The purpose of the study is to compare the pharmacokinetics and relative bioavailability of medroxyprogesterone in healthy female participants following subcutaneous injection of Sayana Press into the upper arm versus anterior thigh and abdomen.

NCT ID: NCT04890457 Recruiting - Healthy Clinical Trials

Brain, Behavior and Endocrine Effects of Transcutaneous Vagus Nerve Stimulation

Start date: March 5, 2021
Phase: N/A
Study type: Interventional

The main aim of the study is to investigate whether the transcutaneous vagus nerve stimulation(tVNS) promotes oxytocin release and the potential biomarkers of tVNS based on eye-tracking data

NCT ID: NCT04885322 Recruiting - Healthy Clinical Trials

Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands

Start date: April 14, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are modulated by transcranial direct current stimulation (tDCS) at frontal and occipital scalp sites. Testing the effects of tDCS at these scalp sites on cognitive task performance will help us understand the roles of the brain regions corresponding to these sites during higher-order cognitive processing (language comprehension, cognitive control, and related attention and memory processes). Behavioral and electrophysiological (EEG) measures will be used to assess cognitive performance. Our overarching hypothesis is that stimulating prefrontal circuits with tDCS can improve cognitive control performance, and ultimately performance on a range of cognitive tasks, as compared to stimulating a different cortical region (occipital cortex) or using sham stimulation. This study is solely intended as basic research in order to understand brain function in healthy individuals and individuals with schizophrenia. This study is not intended to diagnose, cure or treat schizophrenia or any other disease.

NCT ID: NCT04881292 Recruiting - Healthy Clinical Trials

RF Based QIMT & QAS Study on Chinese Adults

Start date: May 1, 2021
Phase:
Study type: Observational

This study intends to establish the normal reference values of carotid artery intima-media thickness and vascular elasticity of Chinese adults based on ultrasound radio frequency technology through a multi-center large-sample study, which provides important information for the risk prediction and prognosis evaluation of Chinese adults' cardiovascular disease.

NCT ID: NCT04880226 Recruiting - Healthy Clinical Trials

A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation

Start date: August 30, 2021
Phase: N/A
Study type: Interventional

The result of these studies will be used to improve patient care through assessment of new technology to determine whether it is beneficial (i.e. improving data acquisition speed or image quality) during iMRI procedures.