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NCT ID: NCT05538949 Completed - Healthy Clinical Trials

Safety, Tolerability and Pharmacokinetics of EB-203 Eye Drops in Healthy Volunteers

Start date: June 29, 2022
Phase: Phase 1
Study type: Interventional

The purpose of study is to evaluate safety, tolerability and pharmacokinetics of EB-203 Drops in adult healthy volunteers. condition/disease : AMD(Age-related Macular Degeneration) Intervention/treatment : EB-203 or Placebo Phase : Phase I

NCT ID: NCT05538312 Completed - Healthy Clinical Trials

A Study to Understand the Effect of Itraconazole on the Levels of a Study Medicine Called ARV-471 in Healthy Adults

Start date: February 23, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to understand if a strong CYP3A4 inhibitor (itraconazole) affects how ARV-471 is processed and eliminated in healthy adults. All participants in this study will receive one dose of ARV-471 alone by mouth in Period 1. In Period 2, everyone will receive itraconazole by mouth once a day for multiple days. Participants will also receive one dose of ARV-471 by mouth. The levels of ARV-471 in Period 1 will be compared to the levels of ARV-471 in Period 2 to determine if the CYP3A4 inhibitor affects how ARV-471 is processed differently in healthy adults.

NCT ID: NCT05536440 Completed - Healthy Clinical Trials

A Study to Learn About Study Medicine Called PF-07261271 in Healthy People

Start date: October 17, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this clinical trial is to learn about the safety and effects of the study medicine PF-07261271 for the potential treatment of Inflammatory Bowel Disease.

NCT ID: NCT05535231 Completed - Healthy Clinical Trials

A Study to Evaluate the Effect of Turmeric in Healthy Participants

Start date: September 24, 2022
Phase: N/A
Study type: Interventional

Turmeric is recognized as a bioactive compound with potential benefits for human health. This study compares the pharmacokinetic profile of the Turmeric test product to a comparator.

NCT ID: NCT05533411 Completed - Healthy Clinical Trials

A Study of Donanemab (LY3002813) in Healthy Chinese Participants

Start date: September 14, 2022
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and tolerability of donanemab (LY3002813) when administered as single dose in healthy Chinese participants. The study will also assess how fast donanemab gets into the blood stream and how long it takes the body to remove it. The study is open to healthy participants. The study will last up to approximately 85 days.

NCT ID: NCT05533073 Completed - Healthy Clinical Trials

Comparative Bioavailability Study Between Etoricoxib and Tramadol, Administered Individually or in Combination

Start date: August 3, 2020
Phase: Phase 1
Study type: Interventional

Study carried out in the Clinical and Analytical Unit of the Department of Pharmacology and Toxicology of the Faculty of Medicine of the Autonomous University of Nuevo León, with the objective of comparing the bioavailability (Cmax, AUC) of an oral formulation containing Etoricoxib 90 mg / Tramadol 50 mg in combination with that of two oral formulations, Etoricoxib 90 mg or Tramadol 50 mg, administered as a single dose, in healthy subjects under fasting conditions.

NCT ID: NCT05531097 Completed - Healthy Clinical Trials

Ascending Single-Dose and Multiple-Dose Study to Evaluate HSK31679 in Healthy Subjects and Subjects With Elevated LDL-C

Start date: February 22, 2022
Phase: Phase 1
Study type: Interventional

This is a Phase I, single-dose and multiple dose escalation clinical trial for HSK31679 conducted in chinese healthy volunteers and LDL-C elevated subjects. The safety, tolerability, food-impact,pharmacokinetics and pharmacodynamics of HSK31679 tablet in healthy volunteers and LDL-C elevated volunteers will be evaluated using a randomized, double-blind, placebo-controlled trial design

NCT ID: NCT05526586 Completed - Healthy Clinical Trials

A Twelve Week Study of Prototypes Mouth Rinses

Start date: August 31, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of two essential oil containing experimental mouth rinse formulations and an essential oil containing mouth rinse compared to a hydroalcohol control mouth rinse for the reduction of gingivitis and plaque when used as an adjunct to tooth brushing during a twelve-week product usage period.

NCT ID: NCT05525468 Completed - Healthy Clinical Trials

A Phase 1 Study of TDM-180935 Following Topical Administration in Healthy Male Subjects

Start date: February 8, 2023
Phase: Phase 1
Study type: Interventional

Multi-center, randomized, double-blind, vehicle-controlled, parallel group, dose escalation study of TDM-180935 following topical administration in healthy male subjects, 18 to 55 years old

NCT ID: NCT05525403 Completed - Healthy Clinical Trials

The Effects of Fatigue on Exercise-Induced Hypoalgesia During a Dynamic Resistance Exercise

Start date: October 28, 2022
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare immediate changes in pain sensitivity (pressure pain threshold) during quiet rest, low fatigue exercise, and high fatigue exercise.