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NCT ID: NCT05800314 Not yet recruiting - Healthy Clinical Trials

Effectiveness of Different Scoring Systems

Start date: November 2023
Phase:
Study type: Observational

1. Assessment of the effectiveness of a validated poisoning specific scoring system (new poisoning mortality [PMS]) and other commonly used scoring systems for all acutely ill patient (Simple clinical score [SCS] and Rapid Emergency Medicine Score [REMS]) at Assiut university hospitals. 2. Comparison between these scoring systems in terms of sensitivity and specificity in both children and adults. 3. Design a toxicological sheet for Assiut poison control center that include this poisoning scoring system so it could help in assessing prognosis of acute poisoned cas

NCT ID: NCT05792020 Not yet recruiting - Healthy Clinical Trials

Safety, Parameterization, and Mechanism of Transcranial Focused Ultrasound

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Through the BrainBox Initiative, investigators propose to study the effects of motor tFUS on Motor Evoked Potentials (MEPs) and GABA and Glutamate Concentrations in the Brain.

NCT ID: NCT05787626 Not yet recruiting - Healthy Clinical Trials

Efficacy of the Transverse Planes Technique in the Diaphragmatic Region in Young Subjects.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

In the present study, 28 healthy young people will be selected, who will be evaluated by a blind investigator regarding the study objectives, and will be randomly included in two groups. The experimental group will consist of 14 subjects who will carry out 1 weekly session of 10 minutes and who will be evaluated just before starting the intervention, after it and at 4 weeks. The control group will be made up of 14 subjects who will be evaluated in the three periods described without the need to carry out the intervention.

NCT ID: NCT05777642 Not yet recruiting - Healthy Clinical Trials

Oxygen Nanobubble Drink Impact on Exercise in Elite Athletes

Start date: April 20, 2023
Phase: N/A
Study type: Interventional

Although the primary organ of gas exchange is the lung, it has been recognized for some time that other organs have a potential role in gas exchange. There is emerging evidence that the gastrointestinal tract may have the capacity to act as an organ of gas exchange. Several recent studies in both animals and humans have indicated that orally administered oxygenated nanobubbles is a safe intervention that can improve tissue oxygenation. Oxygen nanobubbles can reduce the hypoxia in tumours when injected, in conjunction with sonodynamic therapy. In mice, researchers have shown a reduction in tumour hypoxia and improved response to sonodynamic therapy occurs even when the oxygen nanobubbles are orally administered. This will be an in vivo randomized, double-blinded, cross-over, placebo-controlled study consisting of rowers. By measuring the time taken by participants to complete a 2000m row after consuming an Oxygen nanobubbles drink, and a placebo drink, the investigators will evaluate the efficacy of the nanobubbles on the exercising ability of the participant.

NCT ID: NCT05771740 Not yet recruiting - Healthy Clinical Trials

Pulmonary Fibrosis Lung Sounds Study

Start date: March 2023
Phase:
Study type: Observational

The goal of this observational study is to test whether it is possible to detect particular lung sounds that are unique to patients with the lung disease pulmonary fibrosis and whether any such sounds could be analysed using machine learning to make diagnosing disease easier. Participants will have a sound detection device placed in different locations on the chest and audio sounds will be recorded for analysis. Researchers will compare audio recordings from clinically diagnosed patients with recordings from healthy controls of a similar age to see whether the sounds are sufficiently different within that age group.

NCT ID: NCT05756335 Not yet recruiting - Healthy Clinical Trials

The Brain Metabolism of Unpredictable Signals

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The investigators will be studying brain glucose and oxygen metabolism using hybrid PET/fMRI imaging to better understand how decoupling between brain glucose and oxygen metabolism relates to the processing of unpredictable sensory signals.

NCT ID: NCT05739916 Not yet recruiting - Healthy Clinical Trials

Phamacokinetics and Safety Profiles of DA-1229_01 5/1000mg in Healthy Subjects at Fed State

Start date: March 30, 2023
Phase: Phase 1
Study type: Interventional

This Phase I clinical study is to evaluate the safety/tolerability and pharmacokinetics of DA-1229_01(5/1000 mg x1 tablets) at fed state.

NCT ID: NCT05739903 Not yet recruiting - Healthy Clinical Trials

Phamacokinetics and Safety Profiles of DA-1229_01 5/1000mg in Healthy Subjects at Fasting State

Start date: March 25, 2023
Phase: Phase 1
Study type: Interventional

This Phase I clinical study is to evaluate the safety/tolerability and pharmacokinetics of DA-1229_01 (5/1000 mg x1 tablets) at fasting state.

NCT ID: NCT05739877 Not yet recruiting - Healthy Clinical Trials

Phamacokinetics and Safety Profiles of DA-1229_01 2.5/500mg in Healthy Subjects at Fed State

Start date: March 17, 2023
Phase: Phase 1
Study type: Interventional

This Phase I clinical study is to evaluate the safety/tolerability and pharmacokinetics of DA-1229_01(2.5/500 mg x1 tablets) at fed state

NCT ID: NCT05739851 Not yet recruiting - Healthy Clinical Trials

Phamacokinetics and Safety Profiles of DA-1229_01 2.5/500mg in Healthy Subjects at Fasting State

Start date: March 18, 2023
Phase: Phase 1
Study type: Interventional

This Phase I clinical study is to evaluate the safety/tolerability and pharmacokinetics of DA-1229_01(2.5/500 mg) at fasting state.