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NCT ID: NCT05976737 Not yet recruiting - Healthy Clinical Trials

Bioequivalence Study of Entacapone,Levodopa and Carbidopa Tablets in Healthy Chinese Subjects

Start date: August 17, 2023
Phase: Phase 1
Study type: Interventional

In this trial, 32 healthy subjects are planned to be enrolled in fasting and 36 healthy subjects are planned to be enrolled in postprandial, and the fasting and postprandial trials will be randomized separately. According to the randomization table, subjects will be randomly assigned to one of the two groups (Group A: TRTR, Group B: RTRT). The washout period (dosing interval) between doses will be at least 5 days. Taking the washout period of 5 days as an example, all subjects will take the corresponding medication according to the randomization table on day 1 of the first cycle trial, day 6 of the second cycle trial, day 11 of the third cycle trial, and day 16 of the fourth cycle trial.

NCT ID: NCT05970601 Not yet recruiting - Healthy Clinical Trials

Effects of Sodium Chloride or Its Substitute Salt Potassium Chloride on Vascular Function

ESCAPE-SALT
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

This is a prospective, monocentric, randomized trial to investigate how sodium chloride or its substitute potassium chloride acutely affects vascular function by ingestion via a salted soup. Furthermore we want to get insights on the pathophysiology by analyzing metabolism and cell function in relation to vascular reaction.

NCT ID: NCT05965843 Not yet recruiting - Healthy Clinical Trials

Intervention, Prognosis and Mechanism of Covid-19 Infection in Patients With Underlying Diseases

Start date: August 2023
Phase:
Study type: Observational

The goal of this observational study is to explore the influence of Covid-19 infection and risk factors of severe outcomes in vulnerable population including patients with chronic liver disease, malignant tumor, autoimmune disease, medical staff. The main questions it aims to answer are: 1. The clinical characteristics of vulnerable population after Covid-19 infection. 2. Risk factors for severe illness in vulnerable groups after infection with the Covid-19. 3. The impact of Covid-19 infection on the progression of underlying diseases. Information of participants will be collected such as gender, age, underlying diseases, medication status, vaccination status, clinical and biochemical indicators. Researchers will compare the mild and severe outcomes after Covid-19 infection to identify the "truly vulnerable" population and explore the potential mechanism and intervention for these population.

NCT ID: NCT05959876 Not yet recruiting - Healthy Clinical Trials

The Effect of Perineal Care Education on Palliative Care Patient' Relatives

Start date: August 15, 2023
Phase: N/A
Study type: Interventional

The aim of this randomized controlled study, which includes pre-test and post-test, is to examine the perineum care education given to caregivers of patients with incontinence and being treated in a palliative care clinic. The basic question it aims to answer is: Does the perineum care training given to the relatives of patients treated in the palliative care clinic have an effect on the level of knowledge about perineum care? Participants will participate in a training activity on perineum care. Researchers will compare whether perineum care training given to relatives of palliative care patients is effective compared to the routine service operation, by using lecture, question-answer and presentation method.

NCT ID: NCT05959369 Not yet recruiting - Healthy Clinical Trials

Investigation of Relationship Between Balance, Core Stabilization and Foot Posture in Kickboxers

Start date: July 18, 2023
Phase: N/A
Study type: Interventional

This study aimed to investigate relationship between balance, core stabilization and foot posture in kickboxers. This descriptive study was planned to be conducted to 40 elite athletes as volunteer.

NCT ID: NCT05953506 Not yet recruiting - Healthy Clinical Trials

Phase 1a Study in Healthy Participants

Start date: July 17, 2023
Phase: Phase 1
Study type: Interventional

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral HS-10506 in Chinese Healthy Subjects.

NCT ID: NCT05940207 Not yet recruiting - Healthy Clinical Trials

A Study of Hydrogen Peroxide-Generating E-bandage Safety

Start date: January 2025
Phase: Phase 1
Study type: Interventional

A novel hydrogen peroxide-generating electrochemical bandage for wound infection treatment and prevention, and wound healing has been developed. The purpose of this research is to gather information on the safety and to confirm lack of toxicity of small hydrogen peroxide-generating e-bandages on normal human skin.

NCT ID: NCT05936411 Not yet recruiting - Healthy Clinical Trials

Organ Interaction Patterns in Healthy Individuals for Improved PET/CT Diagnostics

Healthy-PET
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The study titled "Study to determine interaction patterns of different organs in healthy volunteers as a basis for better patient diagnostics using PET/CT imaging" is designed to investigate the interaction patterns of different organs in healthy volunteers. The information gathered is intended to be leveraged to enhance patient diagnostics using PET/CT imaging techniques.

NCT ID: NCT05922189 Not yet recruiting - Healthy Clinical Trials

The Effect of the SBS Decompression Technique on Gastrointestinal Symptoms During the Menstrual Cycle

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Determining the effects of a single application of the sphenobasilar synchondrosis (SBS) decompression technique, on gastrointestinal symptoms during the menstrual cycle is an area that lacks of evidence and proper studies. Therefore the investigators consider this an interesting topic to study.

NCT ID: NCT05917002 Not yet recruiting - Healthy Clinical Trials

MPFC Theta Burst Stimulation as a Tool to Affect Rational Decision Making

Start date: August 1, 2024
Phase: Early Phase 1
Study type: Interventional

This is a study to investigate if a device that temporarily changes brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how healthy participants make decisions. This study involves 2 visits to MUSC that will each take between 2-3 hours. This study is not a treatment study, but it could help inform studies investigating treatment in the future. Participants in this study will be compensated for their time.