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Clinical Trial Summary

The aim of this study was to evaluate the effect of Intestinal microecology after high dose dual therapy combined with probiotics for Helicobacter pylori eradication


Clinical Trial Description

The combination of vonoprazan (VPZ) and amoxicillin (VA therapy) has been shown to achieve notable eradication rates for Helicobacter pylori (H. pylori). Patients who receive this treatment are prone to adverse reactions, such as diarrhea, abdominal distention. We plan to combine probiotic therapy with the above treatment. However, it is not clear what changes in gut microbiota and metabolism may result from this therapy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06292546
Study type Interventional
Source Zhongshan Hospital (Xiamen), Fudan University
Contact Keng Li, Master
Phone 86-592-3501990
Email li.keng@zsxmhospital.com
Status Not yet recruiting
Phase N/A
Start date April 1, 2024
Completion date September 1, 2024

See also
  Status Clinical Trial Phase
Recruiting NCT02576236 - Therapeutic Trial Comparing Triple Therapy Guided by the PCR Detection of Clarithromycin Resistance vs Empiric Concomitant Quadruple Therapy for Helicobacter Pylori Infection N/A