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Glaucoma clinical trials

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NCT ID: NCT03852810 Completed - Glaucoma Clinical Trials

Satisfaction With XEN Gel Stent Versus Trabeculectomy for the Treatment of Glaucoma

XENPRO
Start date: February 25, 2019
Phase:
Study type: Observational

This is a prospective, observational, non-interventional study of patients scheduled to receive surgical intervention either via XEN or trabeculectomy for open-angle glaucoma. The decision to treat patients with a particular surgical procedure will not be influenced by the study as the treatment decision will continue to be made by the patient and the clinician. There will be no study mandated visits or treatments.

NCT ID: NCT03844945 Completed - Ocular Hypertension Clinical Trials

Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan

Start date: March 19, 2019
Phase: Phase 2
Study type: Interventional

Test ocular hypotensive efficacy and systemic safety of netarsudil 0.01%, 0.02%, 0.04% relative to placebo in subjects with open-angle glaucoma or ocular hypertension in Japan

NCT ID: NCT03825380 Completed - Glaucoma Clinical Trials

Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous Patients

Start date: November 23, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of T4032 versus Lumigan.

NCT ID: NCT03822559 Completed - Clinical trials for Open-angle Glaucoma, Ocular Hypertension

A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension

Start date: January 20, 2019
Phase: Phase 3
Study type: Interventional

The objective of this study is to investigate whether the IOP (intraocular pressure) -lowering effect of DE-111A (preservative-free fixed dose combination of 0.0015% tafluprost and 0.5% timolol eye drops, administered one drop a time, once daily for 3 months) is superior to the monotherapy of tafluprost 0.0015% eye drops administered one drop a time, once daily for 3 months) in subjects with open-angle glaucoma or ocular hypertension in China as well as comparison of safety.

NCT ID: NCT03808688 Completed - Ocular Hypertension Clinical Trials

Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting

Start date: December 27, 2018
Phase: Phase 4
Study type: Interventional

To evaluate the IOP lowering efficacy of netarsudil ophthalmic solution 0.02% when used as monotherapy or when used concomitantly with other IOP-lowering agents in subjects with elevated IOP due to open angle glaucoma or ocular hypertension in a real-world clinical setting. The study is an open-label design. The patients will receive treatment for 12 weeks.

NCT ID: NCT03807869 Completed - Glaucoma Clinical Trials

Reduction of Intraocular Pressure After I-stent By-pass Implantation in Eyes With Open Angle Glaucoma

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Purpose of this study is to exam the hypotensive effectiveness of I-stent implantation depended on number of antiglaucoma eye drops at baseline.

NCT ID: NCT03804684 Completed - Clinical trials for Glaucoma, Open-Angle

visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated Perimetry

Start date: January 8, 2019
Phase: N/A
Study type: Interventional

To determine age-adjusted reference values of the visuALL Field Analyzer (vFA) retinal sensitivity and to assess the repeatability of the measured values and compare them with those measured by a Standard Automatic Perimetry (SAP).

NCT ID: NCT03800589 Completed - Clinical trials for Glaucoma, Open-Angle

Assessment of Effectiveness Ex-Press Surgery Modification

Start date: December 1, 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to compare the effectiveness and safety profile of ExPress implantation versus partial deep sclerectomy combined with ExPress implantation with simultaneously phacoemulsification.

NCT ID: NCT03797846 Completed - Glaucoma Clinical Trials

Comparison of Fixation Suture Type in Glaucoma Surgery

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effectiveness and safety of two types of intraoperative eye fixation: for the superior rectus muscle and traction suture in the peripheral cornea. This is a prospective randomized trial with a 6 month follow-up period, which covers patients with open angle glaucoma qualified for combined glaucoma procedure (phacotrabeculectomy). In I group, the intraoperatively fixation in the peripheral part of the cornea is used, in II group the bridle suture for the superior rectus muscle is performed.

NCT ID: NCT03797469 Completed - Clinical trials for Glaucoma, Open-Angle

Nutritional Supplements and Performance During Visual Field Testing (B3 Vitamin)

Start date: April 15, 2019
Phase: N/A
Study type: Interventional

This study seeks to test whether these over-the-counter nutritional supplements have an impact on patients' performance during visual field testing.