Clinical Trials Logo

Glaucoma, Open-Angle clinical trials

View clinical trials related to Glaucoma, Open-Angle.

Filter by:

NCT ID: NCT03104621 Completed - Clinical trials for Primary Open-angle Glaucoma

Efficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma Patients

Start date: March 2013
Phase: Phase 4
Study type: Interventional

The aim of this work is to evaluate efficacy and tolerability of preservative containing 0.0015% tafluprost and preservative-free 0.0015% tafluprost. Both preservative containing and preservative-free 0.0015% tafluprost will reduce intraocular pressure significantly. In addition, preservative-free 0.0015% tafluprost might improve tolerability of glaucoma patients.

NCT ID: NCT03065036 Completed - Clinical trials for Primary Open Angle Glaucoma

Safety and Efficacy Study of the Hydrus Aqueous Implant in Subjects With POAG

POAG
Start date: March 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the ocular hypotensive effect of the Hydrus Aqueous Implant (Standard and Low-Profile), as determined by the change in IOP from baseline (preoperative) and change in the number of glaucoma medications from baseline.

NCT ID: NCT03021629 Completed - Clinical trials for Vitamin D Deficiency

Comparison of Vitamin D Status and Vitamin D Receptor Polymorphisms in Patients With High Myopia and Primary Open-angle Glaucoma

Start date: July 2013
Phase: N/A
Study type: Observational

Vitamin D deficiency is known to be significantly associated with high myopia. This study investigated the vitamin D status in patients with high myopia and primary open-angle glaucoma, in order to understand the relationship between high myopia and the development of primary open-angle glaucoma.110 primary open-angle glaucoma patients, 110 high myopia patients and 110 age-matched people in the Han population were enrolled. Serum levels of 1a, 25-Dihydroxyvitamin D3 were measured by an enzyme-linked immuno-absorbent assay.Vitamin D receptor polymorphic analysis was studied by polymerase chain reaction-restriction fragment length polymorphism technique.

NCT ID: NCT02981446 Completed - Clinical trials for Open Angle Glaucoma or Ocular Hypertension

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Start date: January 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the intraocular pressure-lowering effect and the safety of DE-117 ophthalmic solution compared with Latanoprost ophthalmic solution in subjects with open angle glaucoma or ocular hypertension.

NCT ID: NCT02959593 Completed - Clinical trials for Primary Open Angle Glaucoma

The Effects of Visior on Ocular Hemodynamics

Start date: January 2017
Phase: N/A
Study type: Interventional

To determine the relationship between the affects of viewing commercially available content through the VISIOR video goggles and ocular blood flow in glaucoma patients and healthy subjects.

NCT ID: NCT02914509 Completed - Ocular Hypertension Clinical Trials

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Start date: November 7, 2016
Phase: Phase 3
Study type: Interventional

The objective of the study is to evaluate evaluate the safety and IOP lowering efficacy of OTX-TP, a sustained release travoprost drug product, placed in the canaliculus of the eyelid in the treatment of subjects with open-angle glaucoma or ocular hypertension

NCT ID: NCT02874846 Completed - Ocular Hypertension Clinical Trials

Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution

Start date: July 2016
Phase: Phase 2
Study type: Interventional

To evaluate effect of Netarsudil Ophthalmic Solution 0.02% on Nocturnal and Diurnal Intraocular Pressure.

NCT ID: NCT02873806 Completed - Open-angle Glaucoma Clinical Trials

Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Agents

Start date: March 2013
Phase: Phase 4
Study type: Interventional

The study objective was to evaluate the intraocular pressure (IOP) lowering effect of two iStent devices in eyes of subjects with primary open-angle glaucoma, washed out of two anti-glaucoma medications (one a Prostaglandin) prior to stent implantation.

NCT ID: NCT02868190 Completed - Open Angle Glaucoma Clinical Trials

Two Second-Generation Trabecular Micro-bypass Stents to Treat Glaucoma Subjects on One Hypotensive Medication

Start date: March 2013
Phase: Phase 4
Study type: Interventional

This study objective is to evaluate the intraocular pressure (IOP) lowering effect of two trabecular micro-bypass stents (iStent inject) in eyes of subjects with primary open-angle glaucoma on one topical hypotensive medication

NCT ID: NCT02863705 Completed - Clinical trials for Glaucoma, Open-Angle

Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)

Start date: July 5, 2016
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate the long-term efficacy and safety of COMBIGAN® (brimonidine tartrate/timolol malate) in patients only using COMBIGAN® (brimonidine tartrate/timolol malate) and also in patients who require additional IOP lowering with LUMIGAN® (bimatoprost) 0.01%.