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Gingivitis clinical trials

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NCT ID: NCT05916521 Completed - Gingivitis Clinical Trials

A Three Month Bleeding-Model Clinical Study

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the gingivitis control benefit of an established stannous fluoride containing toothpaste relative to a negative control dentifrice.

NCT ID: NCT05916508 Completed - Gingivitis Clinical Trials

A Bleeding-Model Clinical Study

Start date: October 19, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the gingivitis control benefit of an established stannous fluoride containing toothpaste relative to a negative control dentifrice.

NCT ID: NCT05889975 Completed - Gingivitis Clinical Trials

The Efficacy of Different Adjunctive Plaque Control Modalities in Orthodontic Patients

Start date: January 9, 2023
Phase: Phase 3
Study type: Interventional

Bacterial plaque is the primary etiological factor for periodontal disease ranging from mild gingival inflammation to severe periodontitis.The fixed appliance can alter the microbial composition of the oral environment.Patients who wear fixed braces must perform optimum oral hygiene techniques .using a regular toothbrush alone for plaque removal is important but it is not adequate;therefore,an Adjunctive Plaque Control such as inter dental brush ,single tufted brush and water irrigator are helpful.the objective of this study To compare the efficacy of water irrigator ,single tufted and interdental brush in reducing gingival inflammation and plaque accumulation and To determine the profile of the salivary (MIF) at base line visit and after 4 weeks of the study .

NCT ID: NCT05868200 Completed - Gingivitis Clinical Trials

Anti-Inflammatory Efficacy of Ginger Containing Dentifrice in the Control of Biofilm Induced Gingivitis

Start date: February 12, 2022
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to test efficiency of using toothpaste containing (Ginger) over a period of three month to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal parameters (Gingival Index (GI), Bleeding on probing (BOP) and modified Quigley-Hein Plaque Index (mQHPI ) in comparison with Colgate total toothpastes in patients with biofilm induced gingivitis.

NCT ID: NCT05866341 Completed - Gingivitis Clinical Trials

Nitrate Consumption and Gingival Inflammation

NITGIN14
Start date: August 1, 2014
Phase: N/A
Study type: Interventional

The aim of this investigation is to evaluate the impact of the 14- day consumption of a nitrate-rich diet on the the extent of gingival inflammation in a cohort of periodontal aftercare patients. Recorded parameters were gingival index, plaque control record, salivary nitrate/nitrite level and vascular parameters

NCT ID: NCT05861206 Completed - Inflammation Clinical Trials

Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases. In this clinical study, Chlorhexidine Gluconate (CHX) was chosen as the positive control group and the clinical and biochemical efficacy of mouthwashes with green tea, white tea and essential oil (EO) as the active ingredients were aimed to be examined comprehensively. Methods: 112 participants with gingivitis were randomly assigned to 4 different groups that different mouthwashes were used for 4 weeks. CHX-MW group (0.12% CHX, as a positive control group), EO-MW group (Listerine), GT-MW group (5% Green tea), and WT-MW group (5% White tea). The effects of the mouthwashes on plaque, inflammation, and dental staining were evaluated by indexed scores at the beginning and the end of the 4th week. In addition, markers related to gingival inflammation (IL-1beta, MMP-8) and oxidative stress (TOS, TAS, OSI (TOS/TAS)) were evaluated on samples from the gingival crevicular fluid.

NCT ID: NCT05853276 Completed - Gingivitis Clinical Trials

Effectiveness of Brush DJ App in Improving Oral Hygiene Compliance of Fixed Orthodontic Patients

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

In this day and age, smartphones are occupying big portions of our lives. Expanding development of mobile applications focusing on delivering behavioral health intervention have intrigued us to know better about their efficacy. Hence the present study was conducted to determine the effectiveness of the Brush DJ app on improving the oral hygiene compliance of patients wearing fixed orthodontic appliances by assessing their gingival status. Null hypothesis: There was no difference in the gingival status and oral hygiene status of patients between verbal oral hygiene instructions and oral hygiene instructions using the Brush DJ app. Research hypothesis: There was a difference in the gingival status and oral hygiene status of patients between verbal oral hygiene instructions and oral hygiene instructions using the Brush DJ app

NCT ID: NCT05812300 Completed - Periodontitis Clinical Trials

Local Injection of Periodontal Pocket Method for the Treatment of Gingivitis

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Preliminary clinical studies have confirmed that injection of freshly prepared HA35 can reduce symptoms and signs of gingivitis or periodontitis. This clinical study is a prospective repeated experiments. The purpose of this study was to verify the effectiveness of HA35 injection therapy.

NCT ID: NCT05805865 Completed - Clinical trials for Gingival Inflammation

Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index

Start date: January 3, 2023
Phase: N/A
Study type: Interventional

Objectives: To assess the change in gingival index (GI) and plaque index (PI) when comparing the use of toothpaste tablets to conventional toothpaste. Methods: 40 participants were randomized into two groups: Colgate's toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (C). Both groups utilized their assigned dentifrice for 2 weeks. A pre and post-assessment measured the GI and PI index. A questionnaire on the use of the product was distributed.

NCT ID: NCT05802628 Completed - Gingivitis Clinical Trials

Salivary Drug Concentration Exploratory Study of Cetylpyridinium Chloride Buccal Tablets

Start date: April 10, 2023
Phase: Phase 4
Study type: Interventional

The study is a single-arm, open-label study to explore the salivary concentration of Cetylpyridinium Chloride Buccal Tablets after single-dose administration in Healthy Subjects