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Gingivitis clinical trials

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NCT ID: NCT02884817 Completed - Gingivitis Clinical Trials

Essential Oil+ELA, Plaque and Gingivitis

Start date: September 2015
Phase: Phase 4
Study type: Interventional

A commercially available mouth rinse with ethyl lauroyl arginate and essential oils claims to have enhanced antimicrobial properties as compared to the traditional essential oil products. The aim of the present study was to compare the plaque and gingivitis inhibiting effect of the commercial product containing essential oils with ethyl lauroyl arginate with one placebo and one negative control in a modified experimental gingivitis model. In three groups of healthy volunteers, experimental gingivitis was induced and monitored over 21 days, simultaneously treated with the commercial test solution, 21.6% hydro-alcohol solution and sterile water respectively. The maxillary right quadrant of each individual received mouthwash only, whereas the maxillary left quadrant was subject to both rinsing and mechanical oral hygiene. Compliance and side effects were monitored at day 7, 14, and 21. Plaque and gingivitis scores were obtained at baseline and at day 21.

NCT ID: NCT02883244 Completed - Gingivitis Clinical Trials

Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis

Start date: December 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of a new interdental cleaning device (Soft-Picks Advanced), as compared to a leading brand floss; and, how ease of use can promote the establishment of a hygienic routine of cleaning interproximal spaces.

NCT ID: NCT02861937 Completed - Healthy Clinical Trials

Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels

Start date: April 2014
Phase: N/A
Study type: Interventional

Human IL-21 is present in gingival crevicular fluid in periodontal health, gingivitis and chronic periodontitis. A significant increase in the concentration of IL-21 in gingival crevicular fluid is observed with an increase in the amount of periodontal destruction. Non- surgical periodontal therapy aided in decrease of GCF IL-21 levels in clinical gingivitis and chronic periodontitis

NCT ID: NCT02836223 Completed - Gingivitis Clinical Trials

Evaluation of the Addition of an Interdental Cleaning Device to Manual Brushing on Gingival Health

Start date: July 2016
Phase: N/A
Study type: Interventional

This study evaluates the addition of an interdental cleaning device paired with a manual toothbrush compared to using a manual toothbrush only. Plaque removal, reduction of gingival bleeding and reduction of gingival inflammation.

NCT ID: NCT02809313 Recruiting - Gingivitis Clinical Trials

Clinical and Microbiological Effects of Lactobacillus Rhamnosus in Treatment of Gingivitis

Start date: March 2016
Phase: Phase 2
Study type: Interventional

The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic sachet as an adjunct to scaling and root planning (SRP). Material and methods: Thirty six gingivitis patients will be recruited and monitored clinically and microbiologically at baseline and 3-6 months after therapy. All patients will receive scaling and periodontal treatment and randomly will be assigned over an experimental (SRP + probiotic, n=18) or control (SRP + placebo, n=18) group. The sachet will be used once per day during 3 months.

NCT ID: NCT02808130 Completed - Clinical trials for Hyperlipidemia, Periodontitis, Gingivitis

OXIDATIVE STRESS MARKERS IN GINGIVAL CREVICULAR FLUID IN PATIENTS WITH PERIODONTAL DISEASE AND HYPERLIPIDEMIA

Start date: January 2013
Phase: N/A
Study type: Observational

we hypothesized that hyperlipidemia as an unfavourable levels of lipoprotein subfractions have deleterious impact on the development of periodontal infection by altering oxidative stres status of periodontal tissues. The aim of this study was therefore to investigate i) effect of hyperlipidemia on oxidative change in GCF content, ie. MDA, PC and TAOC levels, in patients with different periodontal status,

NCT ID: NCT02801773 Recruiting - Gingivitis Clinical Trials

Clinical Effect of Lactobacillus Reuteri in Treatment of Gingivitis

Start date: June 2016
Phase: Phase 2
Study type: Interventional

The aim of this randomized placebo- controlled clinical trials is to evaluate the effects of Lactobacillus reuteri containing probiotic lozenges as an adjunct to scaling and root planning (SRP). Material and methods: Thirty six gingivitis patients will be recruited and monitored clinically at baseline, 3 and 6 month after therapy. All patients will receive scaling and periodontal treatment and randomly will be assigned over an experimental (SRP + probiotic, N=18) or control (SRP+ placebo, n=18) group. The lozenges will be used once per day during 3 month.

NCT ID: NCT02775019 Completed - Gingivitis Clinical Trials

Health Impact of L.Reuteri Consumption in Crew Members of a Naval Ship at Sea

NAVLAC16
Start date: May 2016
Phase: N/A
Study type: Interventional

This study is designed to evaluate the impact of the regular consumption of probiotic Lactobacillus reuteri-containing lozenges over a period of 42 days on parameters of oral and general health in crew members of a naval ship at sea.

NCT ID: NCT02750943 Completed - Gingivitis Clinical Trials

Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease

Start date: November 1, 2015
Phase: N/A
Study type: Interventional

This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis. This study will evaluate the efficacy of a dentifrice containing 0.454% weight by weight (w/w) stannous fluoride to control gingivitis and gingival bleeding following 12 weeks twice daily brushing, compared to a negative control dentifrice.

NCT ID: NCT02725983 Completed - Health Behavior Clinical Trials

Intra-oral Camera in Gingival Health

Start date: June 2014
Phase: N/A
Study type: Interventional

Evaluate the effects of using an intra-oral camera (IOC) during supportive periodontal therapy (SPT), on the psychological, behavioral and clinical parameters of patients with gingivitis, outlined by evidence and a theory-based framework.